36341-25-0
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
CAS: 36341-25-0
Molecular Formula: C14H11NO2S
36341-25-0 - Names and Identifiers
36341-25-0 - Physico-chemical Properties
| Molecular Formula | C14H11NO2S |
| Molar Mass | 257.31 |
| Storage Condition | 2-8°C |
| In vitro study | YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells. YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells. Cell Proliferation Assay Cell Line: MCF-7 and MDA-MB-231 cells Concentration: 0.001, 0.01, 0.1, 1, 10 μM Incubation Time: 96 hours Result: Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC 50 =85.8 nM and 4.02 μM, respectively). |
| In vivo study | YL-109 (15 mg/kg; s.c. for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo. Animal Model: BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells Dosage: 15 mg/kg Administration: S.c. every 2 days for 63 days Result: Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells. |
36341-25-0 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.886 ml | 19.432 ml | 38.864 ml |
| 5 mM | 0.777 ml | 3.886 ml | 7.773 ml |
| 10 mM | 0.389 ml | 1.943 ml | 3.886 ml |
| 5 mM | 0.078 ml | 0.389 ml | 0.777 ml |
Last Update：2024-01-02 23:10:35
36341-25-0 - Reference Information
| biological activity | YL-109 is a new anti-tumor reagent, which can inhibit the growth and invasion of breast cancer cells in vitro and in vivo. |
| in vitro study | YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells. YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells. Cell Proliferation Assay Cell Line: MCF-7 and MDA-MB-231 cells Concentration: 0.001, 0.01, 0.1, 1, 10 μ m Incubation Time: 96 hours Result: Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC 50=85.8 nM and 4.02 μ m, respectively). |
| Cell Line: | MCF-7 and MDA-MB-231 cells |
| Concentration: | 0.001, 0.01, 0.1, 1, 10 μM |
| Incubation Time: | 96 hours |
| Result: | Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC 50 =85.8 nM and 4.02 μM, respectively). Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells. |
| in vivo study | YL-109 (15 mg/kg; S.c. for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo. Animal model: BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells Dosage: 15 mg/kg Administration: S.c. every 2 days for 63 days result: Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells. |
| Animal Model: | BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells |
| Dosage: | 15 mg/kg |
| Administration: | S.c. every 2 days for 63 days |
Last Update：2024-04-09 21:04:16
Supplier List
Spot supply
Product Name: YL-109 Request for quotationCAS: 36341-25-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-(4-hydroxy-3-methoxyphenyl)benzothiazole Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: YL-109 Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: YL-109 Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Visit Supplier Webpage Request for quotation
CAS: 36341-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 36341-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: YL-109 Request for quotationCAS: 36341-25-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-(4-hydroxy-3-methoxyphenyl)benzothiazole Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: YL-109 Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: YL-109 Visit Supplier Webpage Request for quotationCAS: 36341-25-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Visit Supplier Webpage Request for quotation
CAS: 36341-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 36341-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
36341-25-0
85817-34-1
Molecular sieves 3A
139726-37-7
Oxadiazon
Phenyl(1-hydroxycyclohexyl)methanone
27317-59-5
82692-96-4
85817-34-1
Molecular sieves 3A
139726-37-7
Oxadiazon
Phenyl(1-hydroxycyclohexyl)methanone
27317-59-5
82692-96-4