26549-65-5
N,N,N',N'-Tetramethyl-L-tartramide
CAS: 26549-65-5
Molecular Formula: C8H16N2O4
26549-65-5 - Names and Identifiers
26549-65-5 - Physico-chemical Properties
| Molecular Formula | C8H16N2O4 |
| Molar Mass | 204.22 |
| Density | 1.2441 (rough estimate) |
| Melting Point | 184-186°C(lit.) |
| Boling Point | 342.71°C (rough estimate) |
| Specific Rotation(α) | 46 º (c=3, EtOH) |
| Flash Point | 198.6°C |
| Solubility | Ethanol (Slightly, Heated), Water (Slightly) |
| Vapor Presure | 3.07E-08mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| BRN | 1959244 |
| pKa | 11.79±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.4500 (estimate) |
| MDL | MFCD00025672 |
| Physical and Chemical Properties | alpha:46 o (c=3, EtOH) |
26549-65-5 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29241990 |
26549-65-5 - Introduction
N,N,N',N'-Tetramethyl-L-tartramide is an organic compound with the chemical formula C10H16N2O4. The following is a description of the nature, use, preparation and safety information of N,N,N',N'-Tetramethyl-L-tartramide:
Nature:
1. Appearance: usually white crystalline powder.
2. Solubility: Soluble in water and polar organic solvents, such as Alcohols, Ketones and esters.
3. Melting point and boiling point: melting point of 118-124 degrees Celsius.
4. Molecular weight: 232.25g/mol.
Use:
N,N,N',N'-Tetramethyl-L-tartramide have a wide range of applications in the field of chemistry. They are mainly used as ligands for chiral catalysts and can promote asymmetric catalytic reactions. It can form complexes with transition metals, which can effectively control the stereoselectivity in the synthesis of compounds and help to synthesize chiral molecules. Therefore, N,N,N',N'-Tetramethyl-L-tartramide are often used in organic synthesis to prepare chiral drugs, pesticides, plant protection agents, etc.
Method:
N,N,N',N'-Tetramethyl-L-tartramide can be prepared by reacting methyl L-tartrate with methylamine. First, methyl 1-tartrate is dissolved under acidic conditions, and an excess amount of methylamine is added for reaction. After the reaction, the product N,N,N',N'-Tetramethyl-L-tartramide can be obtained by distillation and purification.
Safety Information:
N,N,N',N'-The use of Tetramethyl-L-tartramide is generally safer. However, as with any chemical, correct experimental procedures should be followed. Care should be taken to avoid contact with strong oxidants and to avoid the production of harmful gases, vapors or fumes. Also, wear appropriate personal protective equipment such as safety glasses and gloves during use. During storage and handling, it should be kept in a dry, low temperature environment, and away from fire and combustible materials. If ingestion or contact with skin, please seek the help of a doctor in time and provide the doctor with relevant chemical information.
Nature:
1. Appearance: usually white crystalline powder.
2. Solubility: Soluble in water and polar organic solvents, such as Alcohols, Ketones and esters.
3. Melting point and boiling point: melting point of 118-124 degrees Celsius.
4. Molecular weight: 232.25g/mol.
Use:
N,N,N',N'-Tetramethyl-L-tartramide have a wide range of applications in the field of chemistry. They are mainly used as ligands for chiral catalysts and can promote asymmetric catalytic reactions. It can form complexes with transition metals, which can effectively control the stereoselectivity in the synthesis of compounds and help to synthesize chiral molecules. Therefore, N,N,N',N'-Tetramethyl-L-tartramide are often used in organic synthesis to prepare chiral drugs, pesticides, plant protection agents, etc.
Method:
N,N,N',N'-Tetramethyl-L-tartramide can be prepared by reacting methyl L-tartrate with methylamine. First, methyl 1-tartrate is dissolved under acidic conditions, and an excess amount of methylamine is added for reaction. After the reaction, the product N,N,N',N'-Tetramethyl-L-tartramide can be obtained by distillation and purification.
Safety Information:
N,N,N',N'-The use of Tetramethyl-L-tartramide is generally safer. However, as with any chemical, correct experimental procedures should be followed. Care should be taken to avoid contact with strong oxidants and to avoid the production of harmful gases, vapors or fumes. Also, wear appropriate personal protective equipment such as safety glasses and gloves during use. During storage and handling, it should be kept in a dry, low temperature environment, and away from fire and combustible materials. If ingestion or contact with skin, please seek the help of a doctor in time and provide the doctor with relevant chemical information.
Last Update：2024-04-09 21:11:58
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View History
26549-65-5
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489471-87-6
BICINCHONINIC ACID
1003710-06-2
158442-41-2
874219-35-9
Black MSRL
1740-54-1
67786-14-5
Benzaldehyde, 4-bromo-2-hydroxy-
489471-87-6
BICINCHONINIC ACID
1003710-06-2
158442-41-2
874219-35-9
Black MSRL