205445-55-2
N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine
CAS: 205445-55-2
Molecular Formula: C14H16F3NO4
205445-55-2 - Names and Identifiers
| Name | N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine |
| Synonyms | BOC-D-PHE(F)3-OH BOC-D-PHE(M,P-F3)-OH BOC-D-PHE(3,4,5-F 3)-OH BOC-D-PHE(3,4,5-TRIFLUORO)-OH BOC-D-3,4,5-TRIFLUOROPHENYLALANINE Boc-D-3,4,5-Trifluorophenylalanine BOC-3,4,5-TRIFLUORO-D-PHENYLALANINE N-(T-BUTOXYCARBONYL)-3,4,5-TRIFLUORO-D-PHENYLALANINE N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine N-ALPHA-T-BUTOXYCARBONYL-D-(3,4,5-TRIFLUOROPHENYL)ALANINE |
| CAS | 205445-55-2 |
| InChI | InChI=1/C14H16F3NO4/c1-14(2,3)22-13(21)18-10(12(19)20)6-7-4-8(15)11(17)9(16)5-7/h4-5,10H,6H2,1-3H3,(H,18,21)(H,19,20)/t10-/m1/s1 |
205445-55-2 - Physico-chemical Properties
| Molecular Formula | C14H16F3NO4 |
| Molar Mass | 319.28 |
| Density | 1.323±0.06 g/cm3(Predicted) |
| Boling Point | 424.4±45.0 °C(Predicted) |
| Flash Point | 210.5°C |
| Vapor Presure | 5.83E-08mmHg at 25°C |
| pKa | 3.71±0.10(Predicted) |
| Storage Condition | Keep Cold |
| Refractive Index | 1.495 |
205445-55-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Harmful/Irritant/Keep Cold |
| Hazard Class | IRRITANT |
205445-55-2 - Introduction
N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine is an organic compound with the following properties:
1. Appearance: White crystalline solid.
2. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
3. Melting Point: about 85-86 ° C.
N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine is widely used in chemical synthesis and is used as a starting material for polypeptide synthesis. Some of its main uses include:
1. Polypeptide synthesis: as a starting material with a trifluorophenylalanine residue in the synthetic polypeptide.
2. Drug development: for the synthesis of biologically active compounds and drugs.
3. Chemical Research: as a reagent and intermediate of organic synthesis reaction.
The preparation method of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine is generally carried out by the following steps:
1. Benzoyl chloride and [[dimethylaminomethyl] tetrafluoroborate (Boc-NHCH2BF3) are reacted in a two-phase system to give the precursor product of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine.
2. The product was purified by high performance liquid chromatography (HPLC) or column chromatography.
However, during Operation and storage, N-(tert-butoxycarbonyl)-3,4, 5-trifluororo-d-phenylalanine requires the following safety information:
1. This compound may be irritating to the eyes, skin and mucous membranes, so appropriate personal protective equipment such as gloves, goggles and laboratory clothing should be worn during operation.
2. Avoid inhaling dust or solution vapor, and ensure that the operation is carried out in a well-ventilated place.
3. Store in a dry, cool and well-ventilated place, away from fire and oxidizing agents.
4. In use, strictly abide by the relevant safety procedures and operating guidelines.
1. Appearance: White crystalline solid.
2. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
3. Melting Point: about 85-86 ° C.
N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine is widely used in chemical synthesis and is used as a starting material for polypeptide synthesis. Some of its main uses include:
1. Polypeptide synthesis: as a starting material with a trifluorophenylalanine residue in the synthetic polypeptide.
2. Drug development: for the synthesis of biologically active compounds and drugs.
3. Chemical Research: as a reagent and intermediate of organic synthesis reaction.
The preparation method of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine is generally carried out by the following steps:
1. Benzoyl chloride and [[dimethylaminomethyl] tetrafluoroborate (Boc-NHCH2BF3) are reacted in a two-phase system to give the precursor product of N-(tert-butoxycarbonyl)-3,4,5-trifluoro-D-phenylalanine.
2. The product was purified by high performance liquid chromatography (HPLC) or column chromatography.
However, during Operation and storage, N-(tert-butoxycarbonyl)-3,4, 5-trifluororo-d-phenylalanine requires the following safety information:
1. This compound may be irritating to the eyes, skin and mucous membranes, so appropriate personal protective equipment such as gloves, goggles and laboratory clothing should be worn during operation.
2. Avoid inhaling dust or solution vapor, and ensure that the operation is carried out in a well-ventilated place.
3. Store in a dry, cool and well-ventilated place, away from fire and oxidizing agents.
4. In use, strictly abide by the relevant safety procedures and operating guidelines.
Last Update：2024-04-09 21:21:28
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Product Name: Boc-3,4,5-trifluoro-D-phenylalanine Visit Supplier Webpage Request for quotationCAS: 205445-55-2
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Mobile: +86-18821248368
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Product Name: Boc-D-2-Amino-3-(3,4,5-trifluoro-phenyl)alanine Request for quotation
CAS: 205445-55-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
CAS: 205445-55-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Spot supply
Product Name: N-Boc-3,4,5-trifluoro-D-phenylalanine Visit Supplier Webpage Request for quotationCAS: 205445-55-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: BOC-D-3,4,5-TRIFLUOROPHENYLALANINE Visit Supplier Webpage Request for quotation
CAS: 205445-55-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 205445-55-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
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