246231-79-8

246231-79-8 - Names and Identifiers

Name	(R)-(-)-1-[(S)-2-Di-t-butylphosphino)ferrocenyl]ethyldi-(4-CF3-phenyl)phosphine
Synonyms	JOSIPHOS SL-J011-1 JOSIPHOS SL-J011-2 (R)-(-)-1-[(S)-2-Di-t-butylphosphino)ferrocenyl]ethyldi-(4-CF3-phenyl)phosphine (R)-(-)-1-[(S)-2-(BIS(4-TRIFLUOROMETHYLPHENYL)PHOSPHINO)FERROCENYL]ETHYL-DI-T-BUTYLPHOSPHINE (S)-1-[(R)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE (R)-1-[(S)-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENYL]-ETHYLDI-TERT-BUTYLPHOSPHINE (R,R)-1-[1-(DI-TERT-BUTYLPHOSPHINO)ETHYL]-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENE (R)-(-)-1-[(S)-(2-DI-TERT-BUTYLPHOSPHINO)FERROCENYL]ETHYLDI-(4-TRIFLUOROMETHYLPHENYL)PHOSPHINE (S,S)-1-[1-(DI-TERT-BUTYLPHOSPHINO)ETHYL]-2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]PHOSPHINO]FERROCENE
CAS	246231-79-8
InChI	InChI=1/C29H33F6P2.C5H5.Fe/c1-19(37(26(2,3)4)27(5,6)7)24-9-8-10-25(24)36(22-15-11-20(12-16-22)28(30,31)32)23-17-13-21(14-18-23)29(33,34)35;1-2-4-5-3-1;/h8-19H,1-7H3;1-5H;/t19-;;/m0../s1

246231-79-8 - Physico-chemical Properties

Molecular Formula	C34H32F6FeP2
Molar Mass	672.41
Specific Rotation(α)	-352° ±10° (c 0.5, CHCl3)
Appearance	Powder
Color	orange
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

246231-79-8 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29319090

246231-79-8 - Introduction

(R)-(-)-1-[(S)-2-Di-t-butylphosphino)ferrocenyl]ethyldi-(4-CF3-phenyl)phosphine is a chiral ligand with the following properties:

1. Appearance: colorless or light yellow solid.

2. Molecular formula: C37H46F3FeP2.

3. Molecular Weight: 652.61.

4. Melting point: About 120-125 ° C.

5. Solubility: Soluble in common organic solvents, such as chloroform, dimethylformamide, etc.

The main use of this compound is as a chiral ligand in organic synthesis. It can be used in combination with asymmetric catalysts in the Catalyst System of organic reactions to improve the selectivity, efficiency and yield of the reaction. In addition, it can also be used in metal organic chemistry, homogeneous catalysis, asymmetric synthesis and other fields.

The compound can be obtained by the following preparation method: reacting di-tert-butyl phosphine with (4-trifluoromethylphenyl) sodium tetrafluoroborate to obtain the corresponding di-tert-butyl-(4-trifluoromethylphenyl) phosphine. Then, this product is reacted with (di-tert-butylphosphino)-ferrocene to introduce a ferrocene group into the molecule, and finally the target compound is obtained.

Due to the lack of sufficient information on the safety of this compound, the current assessment of its toxicity and danger is still limited. Therefore, when using and operating the compound, the safety operation procedures of the chemical laboratory should be strictly observed, and corresponding protective measures should be taken, such as wearing protective glasses, wearing chemical protective clothing, gloves, etc, avoid direct contact with skin, eyes and inhalation. At the same time, store it in a dry, cool place, and away from fire and oxidizing agents. If an accident occurs carelessly, appropriate emergency measures should be taken quickly and professional advice should be consulted.

Last Update：2024-04-10 22:29:15