144688-70-0
(R)-1-Boc-2-cyanopyrrolidine
CAS: 144688-70-0;228244-20-0
Molecular Formula: C10H16N2O2
144688-70-0 - Names and Identifiers
144688-70-0 - Physico-chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molar Mass | 196.25 |
| Density | 1.08±0.1 g/cm3(Predicted) |
| Melting Point | 32-37℃ |
| Boling Point | 307.9±35.0 °C(Predicted) |
| Flash Point | >110℃ |
| Vapor Presure | 0.000703mmHg at 25°C |
| pKa | -4.97±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture & Light Sensitive |
| Refractive Index | 1.488 |
| MDL | MFCD06411382 |
| Physical and Chemical Properties | WGK Germany:3 |
144688-70-0 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29339900 |
144688-70-0 - Introduction
(R)-1-Boc-2-cyanopyrrolidine is an organic compound whose chemical properties mainly include:
1. Structural characteristics: It is a chiral compound with (S)-and (R)-Two enantiomers. The molecule contains Boc protecting group (tert-butoxycarbonyl), cyano and pyrrole ring structure.
2. Physical properties:(R)-1-Boc-2-cyanopyrrolidine is colorless to white crystal or powder, soluble in most organic solvents, such as ether, methanol, etc.
3. Use: it is an important intermediate in the synthesis of organic compounds, commonly used in the preparation of drugs, pesticides and bioactive molecules. Its cyano group can be further reacted for the construction of carbon-carbon and carbon-nitrogen bonds, C- C and C- N building reactions.
4. Preparation method: mainly obtained by reaction of cyano group and Boc protecting group on pyrrole ring. (R)-1-Boc-2-cyanopyrrolidine can be obtained by reacting lithium cyanate with sodium cyanate at (-40°C) and then reacting with the Boc-OSuccinimid group.
1. Structural characteristics: It is a chiral compound with (S)-and (R)-Two enantiomers. The molecule contains Boc protecting group (tert-butoxycarbonyl), cyano and pyrrole ring structure.
2. Physical properties:(R)-1-Boc-2-cyanopyrrolidine is colorless to white crystal or powder, soluble in most organic solvents, such as ether, methanol, etc.
3. Use: it is an important intermediate in the synthesis of organic compounds, commonly used in the preparation of drugs, pesticides and bioactive molecules. Its cyano group can be further reacted for the construction of carbon-carbon and carbon-nitrogen bonds, C- C and C- N building reactions.
4. Preparation method: mainly obtained by reaction of cyano group and Boc protecting group on pyrrole ring. (R)-1-Boc-2-cyanopyrrolidine can be obtained by reacting lithium cyanate with sodium cyanate at (-40°C) and then reacting with the Boc-OSuccinimid group.
Last Update：2024-04-09 02:00:42
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Product Name: R-(+)-1-Boc-2-pyrrolidinecarbonitrile Visit Supplier Webpage Request for quotationCAS: 228244-20-0
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Email: product@acmec-e.com
Mobile: +86-18621343501
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Product Name: (R)-(+)-1-Boc-2-cyanopyrrolidine Visit Supplier Webpage Request for quotationCAS: 228244-20-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
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Product Name: (R)-(+)-1-Boc-2-pyrrolidinecarbonitrile Visit Supplier Webpage Request for quotationCAS: 228244-20-0
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View History
144688-70-0
[NH2Me2][(RuCl((S )-xylbinap))2(μ-Cl)3]
Methylglyoxal
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[NH2Me2][(RuCl((S )-xylbinap))2(μ-Cl)3]
Methylglyoxal
丙酸二酸甲酯氯
2-乙基苯硫酚
1544500-13-1
聚偏二氯乙烯
141942-85-0
邻硝基异丙基苯
1028206-60-1