119768-44-4
N-BOC-(R)-1-AMINO-2-PROPANOL
CAS: 119768-44-4
Molecular Formula: C8H17NO3
119768-44-4 - Names and Identifiers
119768-44-4 - Physico-chemical Properties
| Molecular Formula | C8H17NO3 |
| Molar Mass | 175.23 |
| Density | 1.025±0.06 g/cm3(Predicted) |
| Boling Point | 276.4±23.0 °C(Predicted) |
| pKa | 12.42±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4460 |
| MDL | MFCD04974338 |
119768-44-4 - Upstream Downstream Industry
| Raw Materials | (R)-(-)-1-Amino-2-propanol Boc-L-Threonine Di-tert-butyl dicarbonate Carbonic acid, bis(1,1-dimethylethyl) ester |
| Downstream Products | Formamide, N-[(1S)-1-methyl-2-phenylethyl]- |
119768-44-4 - Introduction
N-BOC-(R)-1-AMINO-2-PROPANOL, also known as N-BOC-(R)-1-AMINO-2-PROPANOL, is an organic compound. Its molecular formula is C8H17NO3 and its molecular weight is 175.23g/mol.
The compound has some of the following properties:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in some organic solvents, such as methanol, dimethylformamide and dimethyl sulfoxide
-Melting point: About 25-27 ° C
-with optical rotation: with optical rotation, the optical rotation is positive
N-BOC-(R)-1-AMINO-2-PROPANOL is mainly used for protecting group reaction in organic synthesis. The BOC Group is a commonly used protecting group that can be used to protect amine groups from unwanted reactions or competing side reactions during the reaction. Such compounds can be used as chiral inducers to control chiral selectivity during synthesis. Commonly used in the synthesis of chiral compounds, pharmaceutical intermediates and drugs.
N-BOC-(R)-1-AMINO-2-PROPANOL can be prepared as follows:
1. Under alkaline conditions, 1-bromopropane and N-BOC-1, 2-propanediamine are reacted to obtain N-BOC-(R)-1-AMINO-2-PROPANOL.
This compound requires safety precautions during use and storage, as follows:
-Avoid contact with skin and eyes. Wear appropriate protective gloves and glasses as necessary.
-Avoid high temperature and fire sources during use and storage.
-Avoid inhaling the gas or vapor of the compound, and operate in a well-ventilated place.
-If taken by mistake or inhaled, seek medical attention immediately and take the compound package to the hospital.
When handling and using chemicals, we must strictly follow the relevant laboratory safety procedures to ensure personal safety and the safety of the laboratory environment.
The compound has some of the following properties:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in some organic solvents, such as methanol, dimethylformamide and dimethyl sulfoxide
-Melting point: About 25-27 ° C
-with optical rotation: with optical rotation, the optical rotation is positive
N-BOC-(R)-1-AMINO-2-PROPANOL is mainly used for protecting group reaction in organic synthesis. The BOC Group is a commonly used protecting group that can be used to protect amine groups from unwanted reactions or competing side reactions during the reaction. Such compounds can be used as chiral inducers to control chiral selectivity during synthesis. Commonly used in the synthesis of chiral compounds, pharmaceutical intermediates and drugs.
N-BOC-(R)-1-AMINO-2-PROPANOL can be prepared as follows:
1. Under alkaline conditions, 1-bromopropane and N-BOC-1, 2-propanediamine are reacted to obtain N-BOC-(R)-1-AMINO-2-PROPANOL.
This compound requires safety precautions during use and storage, as follows:
-Avoid contact with skin and eyes. Wear appropriate protective gloves and glasses as necessary.
-Avoid high temperature and fire sources during use and storage.
-Avoid inhaling the gas or vapor of the compound, and operate in a well-ventilated place.
-If taken by mistake or inhaled, seek medical attention immediately and take the compound package to the hospital.
When handling and using chemicals, we must strictly follow the relevant laboratory safety procedures to ensure personal safety and the safety of the laboratory environment.
Last Update：2024-04-09 19:05:55
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View History
Raw Materials for 119768-44-4
(R)-(-)-1-Amino-2-propanol
Boc-L-Threonine
Di-tert-butyl dicarbonate
Carbonic acid, bis(1,1-dimethylethyl) ester
Boc-L-Threonine
Di-tert-butyl dicarbonate
Carbonic acid, bis(1,1-dimethylethyl) ester
Downstream Products for 119768-44-4