1163707-53-6

1163707-53-6 - Names and Identifiers

Name	3,3,3-Trifluoro-2,2-dimethyl-propionyl chloride
Synonyms	3,3,3-trifluoro-2,2-diMethylpropanoyl chloride 3,3,3-Trifluoro-2,2-dimethyl-propionyl chloride Propanoyl chloride, 3,3,3-trifluoro-2,2-dimethyl-
CAS	1163707-53-6

1163707-53-6 - Physico-chemical Properties

Molecular Formula	C5H6ClF3O
Molar Mass	174.55
Density	1.283±0.06 g/cm3(Predicted)
Boling Point	94.0±35.0 °C(Predicted)

1163707-53-6 - Introduction

3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is an organic compound with the chemical formula CF3COC(CH3)2Cl. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Density: 1.368g/cm³
-Boiling Point: 83-85°C
-Melting Point:-69°C
-Solubility: Soluble in organic solvents such as ether and alcohol, react with water to generate harmful gases

Use:
3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is an important organic synthesis reagent, which is commonly used in chemical protection and substitution reactions in organic synthesis reactions. It can be used for the preparation of compounds with pharmacological and agro-pharmaceutical applications, such as glyphosate, triazuron, flurbiprofen and the like.

Method:
3,3, 3-Trifluoro-2, 2-dimethylpropanoyl chloride can be prepared by the following steps:
1. First, 2,2-dimethylpropionyl chloride is reacted with trifluoromethanesulfonic acid to generate 3,3, 3-trifluoro-2, 2-dimethylpropionyl trifluoromethanesulfonate.
2. The resulting triflate was then treated with sodium chloride to remove the triflate group to give 3,3, 3-trifluoro-2, 2-dimethylpropanoyl chloride.

Safety Information:
- 3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is irritating and should be avoided in contact with the skin, eyes and respiratory system.
-When in use, should be carried out in a well-ventilated place, and wear appropriate protective equipment, such as chemical protective glasses, gloves and protective clothing.
-In case of accidental inhalation or contact, wash the affected area immediately and seek medical help.
-Waste disposal shall comply with local regulations and shall not be dumped.

Last Update：2024-04-10 22:29:15