阿奇沙坦侧链

阿奇沙坦侧链 - Names and Identifiers

Name	1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-
Synonyms	DMDO-OH AZATMint-D 4-(hidroxiMetil)-5-Metil-1,3-dioxol-2-one 4-hydroxymethyl-5-methyl-1,3-dioxol-2-one 4-(hidroximetil)-5-metil-1,3-dioxol-2-one 4-(hidroximetil)-5-metil-1,3-dioxol-2-ona 4-(hydroxymethyl)-5-methyl-l,3-dioxol-2-one 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one 4-(HydroxyMethyl)-5-Methyl-[1,3]dioxol-2-one 1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl- 4-Methyl-5-hydroxyMethyl-2-oxo-1,3-dioxol-4-ene 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one(DMDO-OH)
CAS	91526-18-0
EINECS	1308068-626-2

阿奇沙坦侧链 - Physico-chemical Properties

Molecular Formula	C5H6O4
Molar Mass	130.1
Density	1.367
Boling Point	214℃
Flash Point	93℃
pKa	14.54±0.10(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C

阿奇沙坦侧链 - Introduction

1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-(abbreviation: HMDH) is an organic compound. The following is a description of the nature, use, preparation and safety information of HMDH:

Nature:
HMDH is a white crystalline solid that is stable at ambient temperatures. Its chemical formula is C6H8O3, and the relative molecular mass is about 128.12g/mol.

Use:
HMDH has a wide range of applications in the chemical industry. It is an important intermediate compound that can be used to synthesize many organic compounds, such as drugs, dyes and pesticides. HMDH is also commonly used as a catalyst for organic synthesis reactions.

Preparation Method:
The preparation method of HMDH is relatively simple and can generally be synthesized by the following routes:
1. Starting from methanol, through alkali-catalyzed peroxidation to formaldehyde;
2. Formaldehyde reacts with sodium hypochlorite under alkaline conditions to produce dioxo methyl tert-butanol;
3. After activation treatment, sodium hydroxide is used as a catalyst to react with oxygen under alkaline conditions to generate HMDH.

Safety Information:
1. HMDH causes irritation in contact with the skin, eyes and respiratory tract. Wear appropriate protective gloves and glasses when using;
2. Avoid inhaling and swallowing HMDH, and avoid spraying dust and solution when using;
3. HMDH is a flammable substance, avoid contact with oxidants and open flames;
4. Refrigerate during storage and place in an airtight container to prevent moisture and air from entering.

Please note that the above information is for reference only. In the actual application process, please follow the relevant safety operation procedures, and carry out necessary safety assessments and measures according to the specific situation.

Last Update：2024-04-09 15:16:21