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茵芋苷标准品

Skimmin

CAS: 93-39-0

Molecular Formula: C15H16O8

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茵芋苷标准品 - Names and Identifiers

Name Skimmin
Synonyms Skimmin
SKIMMIN
6‘-succinylskimmin
UMBELLIFERONE GLUCOSIDE
7-(β-D-Glucopyranosyloxy)coumarin
Umbelliferone, beta-D-glucopyranoside
HYDROXYCOUMARIN-7-GLUCOSIDE, 7-(SKIMMIN)(P)
7-(β-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
CAS 93-39-0
EINECS 200-158-5

茵芋苷标准品 - Physico-chemical Properties

Molecular FormulaC15H16O8
Molar Mass324.28
Density1.588
Melting Point221-222℃
Boling Point422.63°C (rough estimate)
Specific Rotation(α)D18 -80° (c = 10 in pyridine)
Solubility Soluble in methanol, DMSO
AppearanceWhite powder or crystal
pKa12.73±0.70(Predicted)
Storage Condition2-8°C
Refractive Index1.5500 (estimate)
MDLMFCD00017710
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Tripterygium wilfordii, taro, claw gold.

茵芋苷标准品 - Reference

Reference
Show more
1. Lu Senhua, Li Qiang, fan Wenyan, Chen Yu, Liu Jicheng. Evaluation of quality of xiaoliuteng from different habitats by HPLC characteristic fingerprint combined with Chemometrics [J]. Modern Chinese medicine research and practice, 2020,34(06):52-56.

茵芋苷标准品 - Reference Information

, also known as 7-o-β-d-glucopyranosyloxycoumarin, enroside is widely distributed in various plants and citrus fruits, and has the activity of treating renal insufficiency. At present, the drugs for the treatment of renal insufficiency are mainly Benazepril and Losartan, but they mainly rely on imports, are expensive, and have large toxic and side effects, such as hyperkalemia, Cough is serious, and the effect of lowering blood pressure is too weak. , can inhibit the deposition of immune complexes, has anti-inflammatory activity.
Introduction
preparation a method for the preparation of enroside, characterized in that the method consists of the following steps: (1) take the whole plant of horseshoe gold, extract 3 times with acetone solution at room temperature, 10-30 minutes each time, combine the extract, reduce pressure and concentrate to extract; (2) the extract was subjected to 15-18 countercurrent extraction with a mixture of ethyl acetate and methanol in a ratio of 10: 1, the extract was combined, and the solvent was recovered under reduced pressure to obtain the extract. (3) the extract was dispersed by adding water, through the polyamide resin column, 30-60% ethanol elution, the eluent is concentrated to obtain crude product; (4) the crude product is dissolved with methanol, and the sample is applied to the medium pressure chromatography column with silica gel mesh 200-300, the mixture was eluted with methanol-dichloromethane, and the eluate of the target component segment was collected, filtered and concentrated, and dried at low temperature to obtain enroside.
biological activity
Use rotiferin is a useful research chemical with neuroprotective effects. Enroside has the effect of protecting renal function and anti-inflammatory.
for content determination/identification/pharmacological experiments. Pharmacological Efficacy: has a better therapeutic effect on diabetic nephropathy
Last Update:2024-04-09 19:05:15
茵芋苷标准品
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MedChemExpress (MCE)
Spot supply
Product Name: Skimmin Visit Supplier Webpage Request for quotation
CAS: 93-39-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Skimmin Visit Supplier Webpage Request for quotation
CAS: 93-39-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Skimmin Visit Supplier Webpage Request for quotation
CAS: 93-39-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Skimmin Visit Supplier Webpage Request for quotation
CAS: 93-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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