芦荟大黄素8-0葡萄糖苷

芦荟大黄素8-0葡萄糖苷 - Names and Identifiers

Name	Aloe-emodin-8-O-beta-D-glucopyranoside
Synonyms	Emodin Impurity 10 Aloe Emodin 8-Glucoside Aloe-emodin -8-O-β-D-glucoside Aloe-emodin-8-O-glucopyranoside Aloe-eModin-8-O-β-D-glucopyranoside aleo-emodin-8-O-β-D-glucopyranoside Aloe-eModin-8-O-beta-D-glucopyranoside Aloe-emodin-8-O-beta-D-glucopyranoside 9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-
CAS	33037-46-6

芦荟大黄素8-0葡萄糖苷 - Physico-chemical Properties

Molecular Formula	C21H20O10
Molar Mass	432.38
Density	1.673±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	236-237℃
Boling Point	829.9±65.0 °C(Predicted)
Solubility	Insuluble (3.5E-3 g/L) (25 °C)
Appearance	Yellow powder
Color	Dark Orange to Dark Brown
pKa	6.48±0.20(Predicted)
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Physical and Chemical Properties	Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Polygonum multiflorum and rhubarb.

芦荟大黄素8-0葡萄糖苷 - Risk and Safety

HS Code

29389090

芦荟大黄素8-0葡萄糖苷 - Reference

Reference

1. Chen Tinggui, Wei Yu Ru, Zhang Liwei. Identification of pancreatic lipase inhibitors in Polygonum cuspidatum by magnetic beads Immobilized enzyme and LC-MS/MS [J]. Natural product research and development, 2017(2).
2. Luo Yiyuan, Liu juanxiu, Wang Feng, etc. Simultaneous determination of 13 components in caulis polygoni multiflori by ultra performance liquid chromatography-tandem mass spectrometry [J]. Chinese Journal of Traditional Chinese Medicine, 2016.
3. Longfei Lin, Hongmei Lin, Miao Zhang, Boran Ni, Xingbin Yin, Changhai Qu, Jian Ni,A novel method to analyze Hematopoietic components in polygnum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectroscopy, Journal
4. Lin, Longfei, et al. "Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro." Biomedicine & Pharmacotherapy 120 (2019): 109531.https://doi.org/10.1016/j.biopha.2019.109531
5. Zhang, Miao, et al. "Interpretation the hepatotoxicity based on pharmacokinetics investigated through oral administrated different extraction parts of Polygonum multiflorum on rats." Frontiers in pharmacology 9 (2018): 505.https://doi.org/10.3389/fphar.201
6. Huang, Juan et al. "Chemical profiles and metabolite study of raw and processed Polygoni Multiflori Radix in rats by UPLC-LTQ-Orbitrap MSn spectrometry." Chinese journal of natural medicines 16.5 (2018): 375-400.https://doi.org/10.1016/S1875-5364(18)30070
7. Lin, Longfei, et al. "Characterization of the constituents in rat plasma after oral administration of radix polygoni multiflori extracts by ultra‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry." Biomedical Chromatography 29.1
8. [IF=3.743] Longfei Lin et al."Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro."Biomed Pharmacother. 2019 Dec;120:109531
9. [IF=3.373] Wanning Chen et al."The composition differences between small black beans and big black beans from different habitats and its effects on the processing of Polygonum multiflorum."Phytochem Analysis. 2021 Sep;32(5):767-779
10. [IF=1.618] Tao Yi et al."Simultaneous Quantitation of Five Bioactive Ingredients in Raw and Processed Fallopia multiflora by Employing UHPLC-Q-TOF-MS."J Chromatogr Sci. 2019 Aug;57(7):618-624
11. [IF=5.645] Huilan Yue et al."Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities."Ind Crop Prod. 2022 Apr;178:114595

芦荟大黄素8-0葡萄糖苷 - Reference Information

Plant Source:	Aloe Vera
biological activity	Aloe-emodin-8-O-β-D-glucopyranoside is a compound isolated from Saussrurea lappa, is a mild human protein tyrosine phosphatase 1B (hPTP1B) inhibitor with an IC50 value of 26.6 μm.
Target	IC50:26.6 μm (hPTP1B)
Use	for content determination/identification/pharmacological experiments

Last Update：2024-04-09 20:52:54

MedChemExpress (MCE)

Multiple SpecificationsSpot supply

Product Name: Aloe-emodin-8-O-β-D-glucopyranoside (Standard) Visit Supplier Webpage Request for quotation
CAS: 33037-46-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898