美他西泮
metaclazepam
CAS: 84031-17-4
Molecular Formula: C18H18BrClN2O
美他西泮 - Names and Identifiers
美他西泮 - Physico-chemical Properties
| Molecular Formula | C18H18BrClN2O |
| Molar Mass | 393.71 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Boling Point | 472.4±45.0 °C(Predicted) |
| pKa | 4.14±0.65(Predicted) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Chemical properties metazepam hydrochloride (Metaclazepam Hydrochlofide):C18H18 BrClN2O?HCI. [61802-93-5]. Crystallized from ethanol, melting point 193-196 ℃. Acute toxicity LD50 mice (mg/kg):1578 oral. |
| Use | Uses benzodiazepine drugs. For antidepressants. |
美他西泮 - Upstream Downstream Industry
| Raw Materials | Dichloromethane 2-Chlorobenzoyl chloride |
美他西泮 - Production method
Compound (I) is acylated with o-chlorobenzoyl chloride to obtain compound (II). Then refluxed with phosphorus oxychloride to obtain a mixture of compound (III) and compound (IV). The mixture is in the presence of sodium methoxide. Refluxed in methanol, all converted to compound (V). Then in dichloromethane, it is brominated in reflux to obtain metazepam.
Last Update：2024-04-09 21:01:54
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CAS: 84031-17-4
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Tel: 18301782025
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Product Name: metaclazepam Visit Supplier Webpage Request for quotation
CAS: 84031-17-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 84031-17-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
美他西泮
2-Amino-4-bromo-5-chloro-3-fluorobenzoic
99-82-1
Quetiapine EP Impurity P (base))
N1-(3-氟苄基)乙烷-1,2-二胺
2,6,7-Trioxabicyclo[2.2.2]octane, 4-(3-fluorophenyl)-1-(4-iodophenyl)-
1-(1-苯基-1H-四唑-5-基)-4-哌啶胺
2H-Cyclohepta[b]furan-2-one, 3,3a,4,5,6,8a-hexahydro-, cis- (9CI)
Carbamic acid, [(2E)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester
6-甲氧基-N-甲基-3-硝基吡啶-2-胺
2-Amino-4-bromo-5-chloro-3-fluorobenzoic
99-82-1
Quetiapine EP Impurity P (base))
N1-(3-氟苄基)乙烷-1,2-二胺
2,6,7-Trioxabicyclo[2.2.2]octane, 4-(3-fluorophenyl)-1-(4-iodophenyl)-
1-(1-苯基-1H-四唑-5-基)-4-哌啶胺
2H-Cyclohepta[b]furan-2-one, 3,3a,4,5,6,8a-hexahydro-, cis- (9CI)
Carbamic acid, [(2E)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester
6-甲氧基-N-甲基-3-硝基吡啶-2-胺
Raw Materials for 美他西泮