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维甲酸维E酯

Tretinoin Tocoferil

CAS: 40516-48-1

Molecular Formula: C49H76O3

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维甲酸维E酯 - Names and Identifiers

Name Tretinoin Tocoferil
Synonyms L 300
N 021
Olcenon
40516-48-1
TOCORETINATE
Tocoretinate (JAN)
Tretinoin Tocoferil
tretinoin tocoferil
Tretinoin tocoferil [INN]
VITAMIN E VITAMIN A ACID ESTER
(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate
O~15~-{(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl}retinoic acid
retinoic acid, O~15~-[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl]-
[2R*(4R*,8R*)]-(±)-Retinoic acid 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester
Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel- (9CI)
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
CAS 40516-48-1
InChI InChI=1/C49H76O3/c1-34(2)19-14-20-35(3)21-15-22-36(4)25-17-31-49(13)32-29-43-42(10)46(40(8)41(9)47(43)52-49)51-45(50)33-38(6)24-16-23-37(5)27-28-44-39(7)26-18-30-48(44,11)12/h16,23-24,27-28,33-36H,14-15,17-22,25-26,29-32H2,1-13H3/b24-16+,28-27+,37-23+,38-33+/t35-,36-,49-/m1/s1

维甲酸维E酯 - Physico-chemical Properties

Molecular FormulaC49H76O3
Molar Mass713.13
Density0.959g/cm3
Boling Point761.3°C at 760 mmHg
Flash Point339.8°C
Vapor Presure4.49E-23mmHg at 25°C
Refractive Index1.523

维甲酸维E酯 - Risk and Safety

ToxicityLD50 in mice (mg/kg): >1000 i.v.; >2000 orally (Fukawa, 1975)

维甲酸维E酯 - Introduction

Tretinoin Tocoferil is a derivative of tretinoin, also known as Tretinoin Tocoferil. The following is a description of its nature, use, preparation and safety information:

Nature:
Tretinoin Tocoferil is a yellow crystalline powder, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. It is unstable under light and easily oxidized.

Use:
Tretinoin Tocoferil are primarily used to treat skin problems such as acne and wrinkles. It has the effect of promoting cell growth and skin cell renewal, is able to improve the texture and color of the skin. In addition, Tretinoin Tocoferil can also be used to treat other skin lesions, such as melanosis and photoaging.

Preparation Method:
The preparation of Tretinoin Tocoferil is mainly carried out by synthetic methods. A common synthetic route is the reaction of retinoic acid with tocopheryl esters to produce Tretinoin Tocoferil.

Safety Information:
Note the following when using Tretinoin Tocoferil:
1. Tretinoin Tocoferil can only be used externally, not orally, to avoid stray into the eyes and mouth.
2. The use of Tretinoin Tocoferil may cause skin irritation and dryness, especially at the beginning of use. The frequency and concentration of use should be gradually increased to reduce discomfort.
3. pregnant women disable Tretinoin Tocoferil, because it may have adverse effects on the fetus.
4. After using Tretinoin Tocoferil, avoid excessive exposure to the sun, because it will increase the sensitivity to ultraviolet rays and cause skin sunburn.
5. During the use of Tretinoin Tocoferil, avoid using other irritating cosmetics or drugs at the same time to avoid adverse reactions.
Last Update:2024-04-09 20:52:54
维甲酸维E酯
Supplier List
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Tocoretinate Visit Supplier Webpage Request for quotation
CAS: 40516-48-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Tocoretinate Visit Supplier Webpage Request for quotation
CAS: 40516-48-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Tocoretinate Visit Supplier Webpage Request for quotation
CAS: 40516-48-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Tocoretinate Visit Supplier Webpage Request for quotation
CAS: 40516-48-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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