甲氧胺盐盐酸
methoxylamine hydrochloride
CAS: 593-56-6
Molecular Formula: CH6ClNO
甲氧胺盐盐酸 - Names and Identifiers
甲氧胺盐盐酸 - Physico-chemical Properties
| Molecular Formula | CH6ClNO |
| Molar Mass | 83.52 |
| Density | 1.1g/mLat 25°C |
| Melting Point | 151-154°C(lit.) |
| Boling Point | 105-110°C |
| Flash Point | 18.2°C |
| Water Solubility | SOLUBLE |
| Solubility | alcohol: soluble(lit.) |
| Vapor Presure | 298mmHg at 25°C |
| Appearance | White-like crystal |
| Color | White to very faint yellow |
| Merck | 14,5989 |
| BRN | 3589723 |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Hygroscopic |
| Refractive Index | n20/D 1.4021 |
| MDL | MFCD00012951 |
| Physical and Chemical Properties | Melting point 148-153°C water-SOLUBLE SOLUBLE |
| Use | Used as a methoxylating agent, but also for the production of the drug cefuroxime side chain and other new drugs |
甲氧胺盐盐酸 - Risk and Safety
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R43 - May cause sensitization by skin contact R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R37 - Irritating to the respiratory system R35 - Causes severe burns |
| Safety Description | S3 - Keep in a cool place. S24 - Avoid contact with skin. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S24/25 - Avoid contact with skin and eyes. S27 - Take off immediately all contaminated clothing. |
| UN IDs | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| RTECS | NC3980000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 2928 00 90 |
| Hazard Note | Corrosive/Hygroscopic |
| Hazard Class | 8 |
| Packing Group | III |
甲氧胺盐盐酸 - Reference
| Reference Show more | 1. Li Geng, Zhao genu, Liu Zi Yu, Zhao genu, Wang Miao, Zhao Chunjie, Xu Haiyan. Determination of isotopic abundance of ~(13)C-labeled amino acids and metabolites in HepG2 cells [J]. Journal of Shenyang Pharmaceutical University, 2020,37(11):990-997. 2. [IF = 5.279] Zhirong Wang et al. bioeffector Pseudomonas fluorescens ZX elicits biosynthesis and accumulation of Functional Ingredients in Citrus Fruit Peel: A Promising Strategy for a More Sustainable Crop.J Agr Food Chem. 2021 |
甲氧胺盐盐酸 - Introduction
Soluble in water and alcohol.
Last Update：2022-10-16 17:26:46
甲氧胺盐盐酸 - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | methoxyamine hydrochloride is an important chemical raw material for the production of cefuroxime octanoic acid (ester) such as antibiotic drugs and phenoxyamine bactericide; Methoxyamine hydrochloride is also a drug, commonly used in surgery to maintain or restore arterial pressure, especially for spinal anesthesia caused by blood pressure reduction. |
| methoxamine hydrochloride | methoxamine hydrochloride also known as O-methylhydroxylamine hydrochloride; Methoxyamine; methoxyamine hydrochloride (OMHA), is an important pharmaceutical, pesticide intermediates, the main uses are as follows: 1, used for color photography and film printing. 2, organic synthesis industry as reducing agent for the preparation of oximes. 3, pharmaceutical field: synthesis of the second generation cephalosporin antibiotics cefuroxime axetil, sulfamethoxazole, and hydroxyurea. 4, pesticide field: synthesis of a new type of high efficiency and low toxicity fungicide phenoxyamine. sodium nitrite method is mostly used in domestic production. ethoxamine hydrochloride, a similar compound of methoxamine hydrochloride, is mainly used in the production of herbicides such as phenoxone, chloradione and dipyrimidine. |
| Use | as a methoxylating reagent, it is also used in the production of new side chain of cefuroxime and other new drugs This product is used as methoxylating reagent for the synthesis of new side chain of cefuroxime and other new medicines and pesticides. used in pharmacy used in the production of cefuroxime octanoic acid (ester) and other antibiotics and phenoxyamine bactericide; Used in the preparation of O-methyl oxime; reagents for the preparation of O-methyl oxime from aldehydes or ketones are protecting ketone groups in 1, 4-dien-3-one systems; derivatizing reagents for detection of steroid keto groups by means of GLC2; Rapid detection of neutral and amino sugars in glycoproteins by means of GC3; Isomeric selective reduction of ketones. |
Last Update：2024-04-09 02:00:09
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View History
甲氧胺盐盐酸
甲基苯并三氮唑钠盐
Chromium Chloride, Hexahydrate
(Z)-丁-2-烯-2-基三氟硼酸钾
Diethylenetriaminepenta(methylenephosphonic) acid
2-甲基-1-(4-(三氟甲硫基)苯氧基)-4-异氰酸酯苯
磷酸化酶 B
Acetic acid, (dodecyloxy)-
1H-Imidazole-4-carboxylic acid, 1-[1-[(1,1-dimethylethoxy)carbonyl]-3-pyrrolidinyl]-
N-F双苯磺酰胺
甲基苯并三氮唑钠盐
Chromium Chloride, Hexahydrate
(Z)-丁-2-烯-2-基三氟硼酸钾
Diethylenetriaminepenta(methylenephosphonic) acid
2-甲基-1-(4-(三氟甲硫基)苯氧基)-4-异氰酸酯苯
磷酸化酶 B
Acetic acid, (dodecyloxy)-
1H-Imidazole-4-carboxylic acid, 1-[1-[(1,1-dimethylethoxy)carbonyl]-3-pyrrolidinyl]-
N-F双苯磺酰胺