Molecular Formula | C21H18O6 |
Molar Mass | 366.36 |
Density | 1.371±0.06 g/cm3(Predicted) |
Melting Point | 263.5-265℃ |
Boling Point | 493.1±45.0 °C(Predicted) |
Solubility | Insuluble (5.1E-3 g/L) (25 °C) |
Appearance | Powder |
pKa | 8.43±0.20(Predicted) |
Storage Condition | 2-8°C |
MDL | MFCD10566621 |
Reference Show more | 1. Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https://doi.org/10.1016/ 2. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;: 3. [IF=4.268] Rui Guo et al."High content screening identifies licoisoflavone A as a bioactive compound of Tongmaiyangxin Pills to restrain cardiomyocyte hypertrophy via activating Sirt3."Phytomedicine. 2020 Mar;68:153171 |
Plant Source: | licorice |
Overview | since ancient times, China has licorice as a medicinal plant. In recent years, it has been found that various flavonoids contained in licorice, including glycyrrhizin, are another kind of natural active substances except glycyrrhizic acid. Licorice flavonoids have many physiological activities, such as anti-microbial, anti-oxidation, anti-ultraviolet and SOD-like effects. More recently found in licorice flavonoids have anti-cancer and anti-AIDS activity. Due to the adverse side effects of synthetic chemicals on the human body, it is a general trend to seek new natural physiological active substances to replace or supplement the finished products. Therefore, many countries have been on licorice flavonoids extraction, purification to expand the scope of the original use of licorice, such as Japan, Israel, China has been on licorice flavonoids extraction, purification. The traditional extraction methods of active components of licorice mainly include hot reflux extraction, Soxhlet extraction, room temperature extraction and microwave-assisted extraction, hot reflux extraction, Soxhlet extraction, the energy consumption of room temperature extraction method is relatively high, the extraction efficiency is relatively low, and the microwave assisted extraction method equipment investment is relatively high, the one-time investment is relatively large, the industrialization scale is restricted. In order to obtain commercial licorice flavonoids. |
biological activity | Neoglycyrol glycyrrhizol was isolated from the roots of Glycyrrhiza uralensis. Neoglycyrol is a traditional patent drug Tongmai Yangxin pill (TMYXP) screening of a potential myocardial protective active compounds. |