Molecular Formula | C10H22ClNO2 |
Molar Mass | 223.74 |
Melting Point | 66-72°C |
BRN | 3696405 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
application | n-octyl aminoacetate hydrochloride can be used as a pharmaceutical intermediate and can be used in laboratory research and development process and chemical medicine synthesis process. |
preparation | 100g of industrial aminoacetic acid, 400ml of n-octanol and 11g of catalyst p-toluenesulfonic acid are added to a three-mouth flask, connected to a water separator, condenser tube and stirrer, heated and heated in gradient, and gallic acid is completely dissolved at a certain temperature, the reaction is carried out at a temperature of 105 ℃ until the end of the reaction is reached when no water is generated (the reaction time is 4 hours). Then the reactants are neutralized, washed, crystallized at low temperature, and vacuum filtered to obtain a white needle-like crystalline crude n-octyl aminoacetate; the crude n-octyl aminoacetate is refined, recrystallized, and vacuum After drying, 81.2g of n-octyl aminoacetate is obtained with a content of 99.3%, and then n-octyl aminoacetate hydrochloride is obtained by adding hydrochloric acid. |