烟酰胺腺嘌呤二核苷酸磷酸单钠盐
Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-d-ribofuranosylpyridinium hydroxide, inner salt, monosodium salt
CAS: 1184-16-3
Molecular Formula: C21H27N7NaO17P3
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Names and Identifiers
| Name | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-d-ribofuranosylpyridinium hydroxide, inner salt, monosodium salt |
| Synonyms | CO II, NA BETA-NADP-NA NADP SODIUM SALT NADP, MONOSODIUM SALT COENZYME II SODIUM SALT BETA-NADP MONOSODIUM SALT Beta-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt beta-Nicotinamide adenine dinucleotide phosphate sodium salt beta-NADP sodium salt Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-d-ribofuranosylpyridinium hydroxide, inner salt, monosodium salt Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate),5',5'-ester with 3-(aminocarbonyl)-1-beta-d-ribofuranosylpyridini um hydroxide, inner salt, monosodium salt |
| CAS | 1184-16-3 |
| EINECS | 214-664-6 |
| InChI | InChI=1/C21H28N7O16P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(45(33,34)35)14(30)11(43-21)6-41-47(38,39)44-46(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1 |
| InChIKey | JNUMDLCHLVUHFS-QYZPTAICSA-M |
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Physico-chemical Properties
| Molecular Formula | C21H27N7NaO17P3 |
| Molar Mass | 765.39 |
| Melting Point | 175-178°C (dec.)(lit.) |
| Water Solubility | Soluble in water. |
| Solubility | H2O: 50mg/mL |
| Appearance | White powder |
| Color | off-white to yellow |
| Merck | 14,6344 |
| BRN | 4779954 |
| Storage Condition | -20°C |
| MDL | MFCD00036973 |
| Use | β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP ) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP :NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. Th |
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Risk and Safety
| Risk Codes | R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | UU3440000 |
| HS Code | 29349990 |
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Reference
| Reference Show more | 1. Sun, Dongxue, et al. "Coupling p-Hydroxybenzoate Hydroaxylase with the Photoresponsive Nanozyme for Universal Dehydrogenase-Based Bioassays." Sensors and Actuators B: Chemical 327 (2021): 128859.https://doi.org/10.1016/j.snb.2020.128859 2. Jin, Yanhong, et al. "Ebselen reversibly inhibits human glutamate dehydrogenase at the catalytic site." Assay and drug development technologies 16.2 (2018): 115-122.https://doi.org/10.1089/adt.2017.822 3. [IF=2.112] Yu Tao et al."Reduction of m-chlorophenacyl chloride coupled with regeneration of NADPH by recombinant Escherichia coli cells co-expressing both carbonyl reductase and glucose 1-dehydrogenase."Ann Microbiol. 2016 Mar;66(1):343-350 |
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Introduction
Soluble in water, methanol, slightly soluble in ethanol, actually insoluble in ether and ethyl acetate.
Last Update：2022-10-16 17:12:28
烟酰胺腺嘌呤二核苷酸磷酸单钠盐 - Reference Information
| introduction | nicotinamide adenine dinucleotide phosphorus is an extremely important nucleotide coenzyme. it is a phosphorylated derivative at the 2 '-position of the ribose ring system linked to adenine in nicotinamide adenine dinucleotide (NAD), which participates in a variety of anabolic reactions, such as the synthesis of lipids, fatty acids and nucleotides. In these reactions, the reduced form of NADP, NADPH, is required as a reducing agent and a negative hydrogen donor. |
| use | pyridinucleotide triphosphate, coenzyme II is a coenzyme widely present in organisms and participates in redox reactions. |
| Synthesis method | Pyridine triphosphate nucleotide, coenzyme II (NADP sodium salt) can be obtained by NADP receiving ATP's γ-phosphate group under kinase catalysis. |
| Biological activity | NADP sodium salt (Sodium NADP), nicotinamide adenine dinucleotide, is a redox cofactor. NADP sodium salt, a key cofactor of electron transfer in metabolism, is alternately oxidized (NADP) and reduced (NADPH). |
Last Update：2024-04-10 22:29:15
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View History
烟酰胺腺嘌呤二核苷酸磷酸单钠盐
偏钨酸铵 水合物
TERT-BUTYL 8-HYDROXY-5-AZASPIRO[3.5]NONANE-5-CARBOXYLATE
ETHYLPYRIDINIUM CHLORIDE
THROMBIN SUBSTRATE III, FLUOROGENIC
PidotiMod IMp.X
KJDZDTDNIULJBE-QXMHVHEDSA-N
2-hydroxyethyl dihydrogenphosphate
托可维A酸
POLY(DIMETHYLSILOXANE), VINYL TERMINATED
偏钨酸铵 水合物
TERT-BUTYL 8-HYDROXY-5-AZASPIRO[3.5]NONANE-5-CARBOXYLATE
ETHYLPYRIDINIUM CHLORIDE
THROMBIN SUBSTRATE III, FLUOROGENIC
PidotiMod IMp.X
KJDZDTDNIULJBE-QXMHVHEDSA-N
2-hydroxyethyl dihydrogenphosphate
托可维A酸
POLY(DIMETHYLSILOXANE), VINYL TERMINATED