氯甲基树脂
Merrifield resin
CAS:
Molecular Formula:
氯甲基树脂 - Names and Identifiers
| Name | Merrifield resin |
氯甲基树脂 - Physico-chemical Properties
| Appearance | Spherical particles |
| Storage Condition | Room Temprature |
氯甲基树脂 - Introduction
Merrifield resin, also known as Merrifield resin, is a polymer resin widely used in solid phase synthesis. Its properties and uses are as follows:
Nature:
-Appearance: usually white granular or powder
-Pore size: It has a larger pore size, which is conducive to the diffusion of reactants and the progress of the reaction
-Chemical stability: It has good chemical stability and is not prone to decomposition under general experimental conditions
-Solubility: It can be well dissolved in organic solvents (such as dimethylformamide, dichloromethane, etc.), and can react with other functional groups
Use:
-Solid phase synthesis: substances used as carriers in solid phase synthesis for the synthesis of peptides, drugs and other small organic molecules
-introduction of active groups: specific functional groups are introduced into the resin through reactions, so as to realize the regulation of polypeptides or small organic molecules
-Separation and purification: Through the principle of adsorption and separation, it can be used for solid phase extraction, purification and separation and purification of target compounds
Preparation Method:
The preparation of Merrifield resin is mainly completed by polymerization and chlorination reaction. First, polystyrene colloidal particles are synthesized by polymerization under acidic conditions. The polymer particles are then chlorinated to introduce chloromethyl functional groups on the resin to form the Merrifield resin.
Safety Information:
When operating the Merrifield resin, pay attention to the following safety precautions:
-Avoid direct inhalation or contact with eyes, skin and clothing when in contact
-Wear appropriate protective equipment such as lab gloves and goggles during operation
-Use it in a well-ventilated place and avoid inhaling dust
-Follow proper laboratory practices and waste disposal programs to avoid pollution or harm to the environment
Nature:
-Appearance: usually white granular or powder
-Pore size: It has a larger pore size, which is conducive to the diffusion of reactants and the progress of the reaction
-Chemical stability: It has good chemical stability and is not prone to decomposition under general experimental conditions
-Solubility: It can be well dissolved in organic solvents (such as dimethylformamide, dichloromethane, etc.), and can react with other functional groups
Use:
-Solid phase synthesis: substances used as carriers in solid phase synthesis for the synthesis of peptides, drugs and other small organic molecules
-introduction of active groups: specific functional groups are introduced into the resin through reactions, so as to realize the regulation of polypeptides or small organic molecules
-Separation and purification: Through the principle of adsorption and separation, it can be used for solid phase extraction, purification and separation and purification of target compounds
Preparation Method:
The preparation of Merrifield resin is mainly completed by polymerization and chlorination reaction. First, polystyrene colloidal particles are synthesized by polymerization under acidic conditions. The polymer particles are then chlorinated to introduce chloromethyl functional groups on the resin to form the Merrifield resin.
Safety Information:
When operating the Merrifield resin, pay attention to the following safety precautions:
-Avoid direct inhalation or contact with eyes, skin and clothing when in contact
-Wear appropriate protective equipment such as lab gloves and goggles during operation
-Use it in a well-ventilated place and avoid inhaling dust
-Follow proper laboratory practices and waste disposal programs to avoid pollution or harm to the environment
Last Update：2024-04-09 21:01:54
Supplier List
Product Name: Merrifield resin Visit Supplier Webpage Request for quotation
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: Merrifield resin Visit Supplier Webpage Request for quotation
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
氯甲基树脂
O-烯丙基-N-(9-蒽甲基)溴化金鸡纳碱
2-氟-5-(氟磺酰基)苯甲酸
Benzenepropanoic acid, 4-hydroxy-b
DIETHYL 2-(5-BROMO-3-CHLOROPYRIDIN-2-YL)MALONATE
2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
5-Cyano-1,4-dihydro-6-methyl-2-[phenylthiomethyl]-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid ethyl ester
甲基 4,6-O-亚苄基-Β-D-吡喃葡萄糖苷
7-(benzo[d][1,3]dioxol-5-ylMethyl)-2-oxa-7-azaspiro[3.5]nonane
1-(对-β-二甲胺基乙氧苯基)-反式-1,2-二苯丁-1-烯,枸椽酸盐
O-烯丙基-N-(9-蒽甲基)溴化金鸡纳碱
2-氟-5-(氟磺酰基)苯甲酸
Benzenepropanoic acid, 4-hydroxy-b
DIETHYL 2-(5-BROMO-3-CHLOROPYRIDIN-2-YL)MALONATE
2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
5-Cyano-1,4-dihydro-6-methyl-2-[phenylthiomethyl]-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid ethyl ester
甲基 4,6-O-亚苄基-Β-D-吡喃葡萄糖苷
7-(benzo[d][1,3]dioxol-5-ylMethyl)-2-oxa-7-azaspiro[3.5]nonane
1-(对-β-二甲胺基乙氧苯基)-反式-1,2-二苯丁-1-烯,枸椽酸盐