巯基聚乙二醇巯基 - Names and Identifiers
巯基聚乙二醇巯基 - Physico-chemical Properties
巯基聚乙二醇巯基 - Introduction
Thiol-PEG-Thiol,HS-PEG-SH(Thiol-PEG-Thiol,HS-PEG-SH) is a chemical compound containing a thiol (-SH) group and a polyethylene glycol (PEG) group in its chemical structure. It has the following properties and uses:
Nature:
- Thiol-PEG-Thiol,HS-PEG-SH is a colorless to light yellow liquid or solid substance.
-It is stable at room temperature and soluble in many organic solvents and water.
-Due to its PEG group, it has good water solubility and biocompatibility.
Use:
- Thiol-PEG-Thiol,HS-PEG-SH are often used as functional compounds in biomedical research and pharmaceutical fields.
-Because its thiol (-SH) group can react with metals, polymers and other compounds with thiol groups, it is commonly used in the preparation of cross-linked hydrogels, nanoparticles and drug carriers.
- Thiol-PEG-Thiol,HS-PEG-SH can be used to modify bioactive molecules, such as proteins, antibodies and enzymes, to improve their stability and pharmacokinetic properties.
Preparation Method:
- Thiol-PEG-Thiol,HS-PEG-SH can be synthesized by introducing thiol (-SH) groups into both ends of polyethylene glycol molecules.
-A common preparation method is to introduce a protecting group through the end of polyethylene glycol, then reduce it to thiol (-SH), and finally remove the protecting group.
Safety Information:
- Thiol-PEG-Thiol,HS-PEG-SH have certain toxicity and irritation, should take appropriate laboratory operation and personal protective measures.
-Avoid direct contact with skin and eyes during use, and wear appropriate personal protective equipment, such as lab gloves and goggles, if necessary.
- Thiol-PEG-Thiol,HS-PEG-SH should be stored in a cool, dry place, and away from fire and oxidizing agents.
-In the process of use and disposal, the relevant chemical handling and waste disposal regulations should be followed.
Last Update:2024-04-09 21:04:16