头孢唑兰中间体二 - Names and Identifiers
Name | (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid
|
Synonyms | ATDA (5-AMINO-[1,2,4]THIADIAZOL-3-YL)-METHOXYIMINO-ACETIC ACID (Z) -2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic 2-METHOXYIMINO-2-(5-ANMINO-1,2,4-THIADIAZOL-3-YL)ACETIC ACID 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-(METHOXYIMINO)ACETIC ACID 2-(5-Amino-1,2,4-Thiadiazol-3-Yl)-2-(Methoxyimino)Acetic Acid (2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)ethanoic acid (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetic acid (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid 2-(5-Boc-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid
|
CAS | 72217-12-0
|
EINECS | 456-150-6 |
InChI | InChI=1/C5H6N4O3S/c1-12-8-2(4(10)11)3-7-5(6)13-9-3/h1H3,(H,10,11)(H2,6,7,9)/b8-2- |
头孢唑兰中间体二 - Physico-chemical Properties
Molecular Formula | C5H6N4O3S
|
Molar Mass | 202.19 |
Density | 1.83 |
Boling Point | 430.4±28.0 °C(Predicted) |
Flash Point | 214.083°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 2.46±0.41(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.749 |
头孢唑兰中间体二 - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
HS Code | 29339900 |
头孢唑兰中间体二 - Introduction
Nature:
-Appearance:(Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acid is white crystalline powder
-melting point: about 190-194 degrees Celsius
-Solubility: Soluble in water and organic solvents such as ethanol and dichloromethane
Use:
- (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid is an important pesticide intermediate. It is often used to synthesize pesticides such as fungicides and herbicides.
Preparation Method:
The synthesis of- (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid can be accomplished in multiple steps. One of the common synthetic methods is the reaction of 5-amino -1, 2,4-thiadiazole-3-carboxylic acid with formaldehyde under alkaline conditions to give N-methyliminoacetate. Then, methanol and excess base were evaporated in the reaction solution to give (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid.
Safety Information:
- (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino acetic acid specific hazard information and safety assessment should be consistent with the relevant data and label information provided by the laboratory or manufacturer. When in use, should follow the corresponding operating procedures and safety measures, such as wearing protective glasses, gloves and laboratory goggles, to ensure a well-ventilated operating environment. In case of accidental contact or inhalation, seek medical attention immediately and provide compound information.
Last Update:2024-04-09 02:00:47