Name | Flavokawain B |
Synonyms | FLAVOKAWIN B FLAVOKAWAIN B Flavokawain B CARDAMONIN-4'-METHYL ETHER 4',6'-DIMETHOXY-2'-HYDROXYCHALCONE DIMETHOXY-2'-HYDROXYCHALCONE, 4',6'- (E)-1-(2-Hydroxy-4,6-dimethoxy-phenyl)-3-phenyl- (E)-1-(2-HYDROXY-4,6-DIMETHOXY-PHENYL)-3-PHENYL-PROPENONE 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one) |
CAS | 1775-97-9 |
Molecular Formula | C17H16O4 |
Molar Mass | 284.31 |
Density | 1.203±0.06 g/cm3(Predicted) |
Melting Point | 85-87°C |
Boling Point | 500.1±50.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Yellow powder |
Color | Yellow to Dark Yellow |
pKa | 6.84±0.40(Predicted) |
Storage Condition | -20°C Freezer |
Physical and Chemical Properties | Pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the root of Piper methysticum Forst of Piper of Piper. |
biological activity | Flavokavain B (Flavokavain B) is a chalcone isolated from the root extract of kava pepper, it is a potent inducer of apoptosis that inhibits the growth of various cancer cell lines. (Flavokavain B) has a strong anti-angiogenic activity. (Flavokavain B) inhibits migration and angiogenesis of human brain endothelial cells (HUVEC) at extremely low non-toxic concentrations. |
Use | for content determination/identification/pharmacological experiments |