匹伐他汀乙酯(消旋)

匹伐他汀乙酯(消旋) - Names and Identifiers

Name	Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate
Synonyms	Ethy(E)-3,5-dihydroxy-7-[2-cycloproyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate Ethyl(E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-hept-6-enoate Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-hept-6-enoate Ethyl(E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate ETHYL (E)-3,5-DIHYDROXY-7-[2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-3-QUINOLINYL]-HEPT-6-ENOATE ethyl (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoater (3R,5S)-Ethyl 7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate ethyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid ethyl ester (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid ethyl ester
CAS	172336-32-2
InChI	InChI=1/C27H28FNO4/c1-2-33-25(32)16-21(31)15-20(30)13-14-23-26(17-9-11-19(28)12-10-17)22-5-3-4-6-24(22)29-27(23)18-7-8-18/h3-6,9-14,18,20-21,30-31H,2,7-8,15-16H2,1H3/b14-13+

匹伐他汀乙酯(消旋) - Physico-chemical Properties

Molecular Formula	C27H28FNO4
Molar Mass	449.51
Density	1.271
Boling Point	670.4±55.0 °C(Predicted)
Flash Point	359.252°C
Vapor Presure	0mmHg at 25°C
pKa	13.79±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.639

匹伐他汀乙酯(消旋) - Introduction

Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate, often referred to simply as FLEC (4-fluorophenylquinoxene Carboxylate).

Nature:
FLEC is an organic compound with a Milky White solid or liquid form. Its chemical formula is C23H24FNO4 and its molecular weight is 395.44g/mol. FLEC is insoluble in water at room temperature, but can be dissolved in some organic solvents, such as ethanol, ether and dichloromethane. It is moderately to highly toxic and requires careful handling.

Use:
FLEC has a wide range of applications. It is used as an intermediate and reagent in organic synthesis and participates in the synthesis of a variety of organic compounds. FLEC is also used in the field of medicine, as the research and development of anti-tumor, anti-virus and anti-bacterial drugs. In addition, FLEC can also be used as a raw material for dyes and optical materials.

Method:
The preparation method of FLEC can be completed by multi-step synthesis. One of the commonly used synthetic route is to first synthesize dihydroxy quinoline, then react with cyclopropyl alcohol, and then obtain the final product FLEC through esterification reaction.

Safety Information:
FLEC is an organic compound and needs to follow certain safe operating regulations. When handling and storing FLEC, avoid contact with skin and eyes, and ensure that it is operated in a well-ventilated environment. Use personal protective equipment, such as lab gloves, goggles, and lab clothes, to reduce potential hazards. At the same time, the FLEC should be stored in a dark, dry, well-ventilated place, away from flammable materials and oxidants.

Please note that this is only a basic introduction to Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate, if you need specific experimental procedures or more detailed information, please refer to the relevant literature or consult a professional.

Last Update：2024-04-09 21:11:58