Molecular Formula | C30H60I3N3O3 |
Molar Mass | 891.53 |
Density | 1.4288 (estimate) |
Melting Point | 235 °C (dec.) (lit.) |
Boling Point | 502.6°C at 760 mmHg |
Flash Point | 125.9°C |
Solubility | DMSO 178 mg/mL Water 178 mg/mL Ethanol <1 mg/mL |
Vapor Presure | 3.13E-10mmHg at 25°C |
Appearance | powder |
Color | Crystals from Me2CO (aq) |
Merck | 13,4364 |
Storage Condition | 2-8°C |
Refractive Index | 1.501 |
MDL | MFCD00011832 |
Physical and Chemical Properties | White or milky white crystalline powder, odorless, slightly bitter, hygroscopic. Mp235 °c. Soluble in water (1:6), slightly soluble in ethanol (1:500), acetone, benzene and chloroform, insoluble in ether. LD50 (mouse, oral) 425mg/kg. |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
RTECS | BS1100000 |
HS Code | 29239000 |
Toxicity | LD50 oral in rabbit: 100mg/kg |
Reference Show more | 1. Xu Shiliang, Wang Shizheng, Xu Rui, et al. Comparison of the effect of several kinds of attractant on snake feeding [J]. Feed industry, 2020, 26 (2):15-19. |
Introduction | galanium iodide is a synthetic non-depolarizing muscle relaxant containing three quaternary ammonium groups. The muscle relaxant effect is similar to that of the Carine, but without blocking the ganglion and releasing histamine, but has a strong atropine-like effect, which can obviously relieve the tension of the vagus nerve and accelerate the heart rate, slightly elevated blood pressure and increased cardiac output. |
preparation | Under the action of potassium hydroxide, pyrogallic acid is formed into sodium salt, and then reacted with diethylaminoethyl chloride and ethyl iodide in sequence. The synthesis reaction formula of the ammonium salt of the iodine is shown in the figure below: Fig. 1 The synthesis reaction formula of the ammonium salt of the salt |
biological activity | Gallamine triethiode is a cholinergic receptor inhibitor with an IC50 of 68.0±8.4 μm. |
Target | Value |
AChR | 68.0 μM |
Use | biochemical research, with muscle relaxation effect. |
production method | Under the action of sodium acetate, pyrogallic acid is formed into sodium salt, and then reacted with diethylaminoethyl chloride and ethyl iodide in sequence. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |