二(2-羟乙基)亚氨基三(羟甲基)甲烷
Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane
CAS: 6976-37-0
Molecular Formula: C8H19NO5
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - Names and Identifiers
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - Physico-chemical Properties
| Molecular Formula | C8H19NO5 |
| Molar Mass | 209.24 |
| Density | 1.346±0.06 g/cm3(Predicted) |
| Melting Point | 104°C(lit.) |
| Boling Point | 466.2±40.0 °C(Predicted) |
| Flash Point | 288°C |
| Water Solubility | soluble |
| Solubility | H2O: 1M at20°C, clear, colorless |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | Crystalline powder |
| Color | Yellow to orange |
| Odor | Odorless |
| Maximum wavelength(λmax) | ['λ: 280 nm Amax: 0.15'] |
| BRN | 2205275 |
| pKa | 6.5(at 25℃) |
| PH | 9.0-10.1 (20-25℃, 1M in water) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Air Sensitive |
| MDL | MFCD00002853 |
| Physical and Chemical Properties | Melting point 103-104°C. Water-soluble. |
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R21/22 - Harmful in contact with skin and if swallowed. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-23 |
| TSCA | Yes |
| HS Code | 29221980 |
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - Reference
| Reference Show more | 1. [IF=10.182] K. Wang et al."Extracting keratin from wool by using L-cysteine."Green Chem. 2016 Jan;18(2):476-481 |
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - A method for the synthesis of Bis-Tris
Abstract:
The present invention provides a method for the synthesis of Bis-Tris, comprising:
step 1. Take 5g of sodium bisulfite and 10 ml of water to prepare the solution, then mix with 50 ml of anhydrous ethanol, and then inject ethylene oxide gas into the mixed solution to make saturated ethylene oxide aqueous solution;
step 2. The saturated solution of 100 ml is heated to 30-35 degrees, then take Tris 60g is poured into this solution and slowly dissolved after 2 hours, 20g of sodium hydroxide and 20 ml of water were added dropwise to the above solution and the pH value of the solution was controlled between 9.5 and 10.0 for 6-8 hours.
step 3. The solution after completion of the reaction in step 2 was vacuum dehydrated, and after hot filtration, anhydrous ethanol was added for dispersion, and the temperature was lowered to wait for precipitation of the product. The method for synthesizing Bis-Tris by using a saturated solution of ethylene oxide is safe and reliable, the reaction is sufficient, and the content of the product is high.
Last Update：2024-01-02 23:10:35
二(2-羟乙基)亚氨基三(羟甲基)甲烷 - Reference Information
| pH range of acid-base indicator discoloration | 5.8 - 7.2 |
| LogP | -2.26 at 20℃ |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | for biological buffer buffer for detection of creatine kinase; also used to effectively protect hemoglobin in freeze-drying; Catholyte, used in IEF/2-D gel electrophoresis. |
Last Update：2024-04-09 21:01:54
Supplier List
Featured ProductsSpot supply
Product Name: Bis(2-Hydroxyethyl)aminotris(hydroxymethyl)methane Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotation
CAS: 6976-37-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 6976-37-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotationCAS: 6976-37-0
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotationCAS: 6976-37-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple SpecificationsSpot supply
Product Name: Bis-Tris (Standard) Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol Request for quotation
CAS: 6976-37-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 6976-37-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Bis-TRIS Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: BIS-TRIS Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: Bis(2-Hydroxyethyl)aminotris(hydroxymethyl)methane Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotation
CAS: 6976-37-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 6976-37-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotationCAS: 6976-37-0
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: Bis[2-Hydroxyethyl] imino Tris-(Hydroxymethyl)-methane Request for quotationCAS: 6976-37-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple SpecificationsSpot supply
Product Name: Bis-Tris (Standard) Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol Request for quotation
CAS: 6976-37-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 6976-37-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Bis-TRIS Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: BIS-TRIS Visit Supplier Webpage Request for quotationCAS: 6976-37-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
二(2-羟乙基)亚氨基三(羟甲基)甲烷
Anti-NEK7 (C-terminal) antibody produced in goat
半咕啉手性配体 1
2,3,4,5,6-无氟苯甲酸钠
5-Amino-3-bromo-2-methylp...
2-[乙基[(十七氟辛基)磺酰]氨基]乙醇聚氧乙烯醚
1,1-二苯基-2-(4-溴苯基)乙烯
5-(甲氧羰基)-3-甲基呋喃-2-羧酸
2-CBZ-2,6-DIAZASPIRO[3.5]NONANE
BIOTINYLAMIDOETHYL]-DITHIOMETHYLENEMALONIC ACID BIS(3-AMINOPROPIONIC ACID)
Anti-NEK7 (C-terminal) antibody produced in goat
半咕啉手性配体 1
2,3,4,5,6-无氟苯甲酸钠
5-Amino-3-bromo-2-methylp...
2-[乙基[(十七氟辛基)磺酰]氨基]乙醇聚氧乙烯醚
1,1-二苯基-2-(4-溴苯基)乙烯
5-(甲氧羰基)-3-甲基呋喃-2-羧酸
2-CBZ-2,6-DIAZASPIRO[3.5]NONANE
BIOTINYLAMIDOETHYL]-DITHIOMETHYLENEMALONIC ACID BIS(3-AMINOPROPIONIC ACID)