乙基3-溴吡啶-4-甲酸酯
ethyl 3-bromopyridine-4-carboxylate
CAS: 13959-01-8
Molecular Formula: C8H8BrNO2
乙基3-溴吡啶-4-甲酸酯 - Names and Identifiers
乙基3-溴吡啶-4-甲酸酯 - Physico-chemical Properties
| Molecular Formula | C8H8BrNO2 |
| Molar Mass | 230.06 |
| Density | 1.501±0.06 g/cm3(Predicted) |
| Boling Point | 263.4±20.0 °C(Predicted) |
| Flash Point | 113.09°C |
| Vapor Presure | 0.01mmHg at 25°C |
| pKa | 0.84±0.18(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.545 |
乙基3-溴吡啶-4-甲酸酯 - Introduction
Ethyl 3-bromopyridine-4-carboxylate is an organic compound with the chemical formula C9H8BrNO2 and a molecular weight of 249.07g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Ethyl 3-bromopyridine-4-carboxylate is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in most organic solvents and is insoluble in water.
-Melting point: Its melting point is about -1°C.
-Boiling point: Its boiling point is about 256-258°C.
Use:
-3-Bromopyridine-4-carboxylic acid ethyl ester is often used as a raw material for organic synthesis.
-It can participate in different reactions, such as Heck reaction, Suzuki reaction, Stille reaction, etc.
-It can also be used to synthesize other organic compounds, such as pesticides and drugs.
Preparation Method:
The preparation method of ethyl 3-bromopyridine-4-carboxylate can be carried out by the following steps:
1. 3-bromopyridine and cuprous bromide are reacted in dimethylformamide (DMF) to form cupric 3-bromopyridine.
2. Under reflux conditions, ethyl formate and stannous carbonate are added to react to generate ethyl 3-bromopyridine-4-carboxylate.
Safety Information:
-3-Bromopyridine-4-carboxylic acid ethyl ester is an organic compound and should be operated in accordance with general laboratory safety procedures.
-It may irritate the eyes, skin and respiratory system, so avoid contact during operation.
-Care should be taken during use, including wearing appropriate protective goggles, gloves and protective clothing.
-During storage and handling, keep the container sealed and store in a cool, dry, and well-ventilated place.
-If inhaled or ingested, seek medical attention immediately. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: Ethyl 3-bromopyridine-4-carboxylate is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in most organic solvents and is insoluble in water.
-Melting point: Its melting point is about -1°C.
-Boiling point: Its boiling point is about 256-258°C.
Use:
-3-Bromopyridine-4-carboxylic acid ethyl ester is often used as a raw material for organic synthesis.
-It can participate in different reactions, such as Heck reaction, Suzuki reaction, Stille reaction, etc.
-It can also be used to synthesize other organic compounds, such as pesticides and drugs.
Preparation Method:
The preparation method of ethyl 3-bromopyridine-4-carboxylate can be carried out by the following steps:
1. 3-bromopyridine and cuprous bromide are reacted in dimethylformamide (DMF) to form cupric 3-bromopyridine.
2. Under reflux conditions, ethyl formate and stannous carbonate are added to react to generate ethyl 3-bromopyridine-4-carboxylate.
Safety Information:
-3-Bromopyridine-4-carboxylic acid ethyl ester is an organic compound and should be operated in accordance with general laboratory safety procedures.
-It may irritate the eyes, skin and respiratory system, so avoid contact during operation.
-Care should be taken during use, including wearing appropriate protective goggles, gloves and protective clothing.
-During storage and handling, keep the container sealed and store in a cool, dry, and well-ventilated place.
-If inhaled or ingested, seek medical attention immediately. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:49:11
Supplier List
Spot supply
Product Name: ETHYL 3-BROMOPYRIDINE-4-CARBOXYLATE Visit Supplier Webpage Request for quotationCAS: 13959-01-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Ethyl 3-bromoisonicotinate Visit Supplier Webpage Request for quotationCAS: 13959-01-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: ETHYL 3-BROMOPYRIDINE-4-CARBOXYLATE Visit Supplier Webpage Request for quotation
CAS: 13959-01-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 13959-01-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: ETHYL 3-BROMOPYRIDINE-4-CARBOXYLATE Visit Supplier Webpage Request for quotationCAS: 13959-01-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Ethyl 3-bromoisonicotinate Visit Supplier Webpage Request for quotationCAS: 13959-01-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: ETHYL 3-BROMOPYRIDINE-4-CARBOXYLATE Visit Supplier Webpage Request for quotation
CAS: 13959-01-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 13959-01-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
乙基3-溴吡啶-4-甲酸酯
N-(1-ADAMANTYL)HYDRAZINECARBOXAMIDE
2-硝基-3-氟苯甲醇
4-氨基-5-溴-2-氯嘧啶
2-[2,4-DICHLORO-5-METHOXY(METHYLSULFONYL)ANILINO]-N-(4-METHOXYPHENYL)ACETAMIDE
2-丁基-1,3-二氮杂螺[4.4]非2-烯-4-酮
THPS-UPC
2-氨基-5-甲基噻唑
(1-(甲基磺酰基)环丙基)甲胺盐酸盐
Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8.beta.)-
N-(1-ADAMANTYL)HYDRAZINECARBOXAMIDE
2-硝基-3-氟苯甲醇
4-氨基-5-溴-2-氯嘧啶
2-[2,4-DICHLORO-5-METHOXY(METHYLSULFONYL)ANILINO]-N-(4-METHOXYPHENYL)ACETAMIDE
2-丁基-1,3-二氮杂螺[4.4]非2-烯-4-酮
THPS-UPC
2-氨基-5-甲基噻唑
(1-(甲基磺酰基)环丙基)甲胺盐酸盐
Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8.beta.)-