tasquinimod
Tasquinimod
CAS: 254964-60-8
Molecular Formula: C20H17F3N2O4
tasquinimod - Names and Identifiers
tasquinimod - Physico-chemical Properties
| Molecular Formula | C20H17F3N2O4 |
| Molar Mass | 406.36 |
| Density | 1.427±0.06 g/cm3(Predicted) |
| Boling Point | 501.5±50.0 °C(Predicted) |
| pKa | 4.50±1.00(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | Tasquinimod inhibits tumor angiogenesis through allosteric inhibition of HDAC4/N-CoR/HDAC3-dependent HIF-1α deacetylation. Tasquinimod also targets infiltrating bone marrow cells and modulates local tumor immunity by blocking the interaction of S100A9 with its ligand receptors (advanced glycation end products and Toll-like receptor 4). |
| In vivo study | In a mouse model of human and rodent prostate cancer, Tasquinimod (30 mg/kg/d p.o.) exhibited anti-angiogenic effects and thus inhibited tumor growth. |
tasquinimod - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.461 ml | 12.304 ml | 24.609 ml |
| 5 mM | 0.492 ml | 2.461 ml | 4.922 ml |
| 10 mM | 0.246 ml | 1.23 ml | 2.461 ml |
| 5 mM | 0.049 ml | 0.246 ml | 0.492 ml |
Last Update：2024-01-02 23:10:35
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Featured ProductsSpot supply
Product Name: Tasquinimod Visit Supplier Webpage Request for quotationCAS: 254964-60-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: ABR-215050 Visit Supplier Webpage Request for quotationCAS: 254964-60-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Tasquinimod Visit Supplier Webpage Request for quotationCAS: 254964-60-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tasquinimod Visit Supplier Webpage Request for quotationCAS: 254964-60-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
tasquinimod
Naphthenic acids, calcium salts
1-Cyclopentene-1-heptanoic acid, 2-chloro-5-oxo-, methyl ester
Pyridine, 3-fluoro-4-(3R)-3-piperidinyl-
1,2-Benzenediol, 3-[2-(1-pyrrolidinyl)ethyl]-
苯正十六酮
Naphthenic acids, calcium salts
1-Cyclopentene-1-heptanoic acid, 2-chloro-5-oxo-, methyl ester
Pyridine, 3-fluoro-4-(3R)-3-piperidinyl-
1,2-Benzenediol, 3-[2-(1-pyrrolidinyl)ethyl]-
苯正十六酮