perhexilinemaleate
rac Perhexiline Maleate
CAS: 6724-53-4
Molecular Formula: C23H39NO4
perhexilinemaleate - Names and Identifiers
perhexilinemaleate - Physico-chemical Properties
| Molecular Formula | C23H39NO4 |
| Molar Mass | 393.56 |
| Melting Point | 181-183°C |
| Solubility | DMSO: ≥5mg/mL |
| Appearance | powder |
| Color | white to tan |
| Storage Condition | 2-8°C |
| In vitro study | At 24, 48 and 72 h of treatment with 0.01 and 1 μM of Perhexiline , NDM29 ncRNA expression level in SH-SY5Y cells is progressively increased, reaching a peak after 48 hours of treatment. Perhexiline treatment increases the susceptibility of NB cells to antiblastic treatments. Co-administration of Perhexiline maleate potentiates the efficacy of cisplatin to reduce the in vitro clonogenic potential of NB cells. |
| In vivo study | The co-administration of Perhexiline and cisplatin yields a clear enhancement of antitumor effects, resulting in a significantly improved progression-free survival as compared with mice treated with DMSO. Perhexiline favors NB cell transition to differentiated phenotype. |
perhexilinemaleate - Risk and Safety
| WGK Germany | 2 |
| RTECS | TM7068000 |
| Toxicity | LD50 in rats, mice (g/kg): >7, 4.37 orally (Causa, Perri) |
perhexilinemaleate - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.541 ml | 12.705 ml | 25.409 ml |
| 5 mM | 0.508 ml | 2.541 ml | 5.082 ml |
| 10 mM | 0.254 ml | 1.27 ml | 2.541 ml |
| 5 mM | 0.051 ml | 0.254 ml | 0.508 ml |
Last Update：2024-01-02 23:10:35
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View History
perhexilinemaleate
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332400-85-8
1210138-46-7
(3-((4-Hydroxypiperidin-1-yl)sulfonyl)-4-methoxyphenyl)boronic acid
21319-18-6
5-Thiazolecarboxylic acid, 2-amino-4-(trifluoromethyl)-, ethyl ester
1-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-1-amine hydrochloride
5-bromo-3-[2-(4-ethylphenyl)-2-oxoethyl]-3-hydroxy-1-methyl-1,3-dihydro-2H-indol-2-one