pentadeuterio-pyrrole - Names and Identifiers
pentadeuterio-pyrrole - Physico-chemical Properties
Molecular Formula | C4H5N
|
Molar Mass | 67.09 |
Density | 1.115 g/mL at 25 °C |
Melting Point | -23 °C |
Boling Point | 131 °C |
Flash Point | 92°F |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.5072(lit.) |
pentadeuterio-pyrrole - Risk and Safety
Risk Codes | R10 - Flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37 - Irritating to eyes and respiratory system.
R41 - Risk of serious damage to eyes
R25 - Toxic if swallowed
R20 - Harmful by inhalation
|
Safety Description | S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39 - Wear suitable gloves and eye/face protection
|
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
pentadeuterio-pyrrole - Introduction
Pyrrole-d5, also known as pyrrolidine diazonium salt dihydrogen salt (Pyridine-d5), is a deuterated pyrrole compound containing 5 deuterium atoms. The following is a description of the properties, uses, preparation and safety information of pyrrole-d5:
Nature:
Pyrrole-d5 is a colorless liquid with a molecular structure similar to pyrrole. Its density is slightly higher than that of water, and its melting and boiling points are approximately -42°C and 115°C, respectively. Pyrrole-d5 is readily soluble in most common organic solvents, but reacts more slowly with alcohol and ether solvents.
Use:
As a deuterated pyrrole compound, pyrrole-d5 is commonly used as a deuterated solvent and a labeling reagent. It is widely used in nuclear magnetic resonance (NMR) studies, as a solvent and as a reference compound. Pyrrole-d5 can provide deuterium atoms for studying the structure and reaction mechanism of samples, and is particularly useful in organic chemistry.
Preparation Method:
Pyrrole-d5 is mainly prepared by chemical reaction. One common method is to use a diazonium salt aminoguanidine coupling agent or an aminoborate to react with an pyrrole compound requiring deuterium displacement. This reaction proceeds via a diazonium salt intermediate to give pyrrole-d5 via cyclization and N-diazotization.
Safety Information:
Pyrrole-d5 is relatively stable, but still need to pay attention to safe operation. It has low toxicity, but still needs to follow laboratory safety procedures for use. Avoid inhalation, ingestion or contact with skin and eyes. Wear appropriate protective safety equipment such as gloves, goggles and clothing when using pyrrole-d5. Handling, storage and disposal are required in accordance with the recommendations on the Safety Data Sheet (MSDS).
Last Update:2024-04-09 15:18:08