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ceritinib

LDK378

CAS: 1032900-25-6

Molecular Formula: C28H36ClN5O3S

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ceritinib - Names and Identifiers

Name LDK378
Synonyms LDK378
LDK 378
ceritinib
Ceritinib
LDK378 Ceritinib
Ceritinib (LDK378)
5-Chloro-N2-[2-isopropoxy-5-Methyl-4-(4-piperidyl)phenyl]-N4-(2-isopropylsulfonylphenyl)pyriMidine-2,4-diaMine
5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine
5-Chloro-N4-[2-[(1-Methylethyl)sulfonyl]phenyl]-N2-[5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyriMidinediaMine
CAS 1032900-25-6
EINECS 811-457-8

ceritinib - Physico-chemical Properties

Molecular FormulaC28H36ClN5O3S
Molar Mass558.14
Density1.251±0.06 g/cm3(Predicted)
Melting Point173-175°C
Boling Point720.7±70.0 °C(Predicted)
Solubility DMSO 20 mg/mL heat Water <1 mg/mL Ethanol 3 mg/mL
AppearanceOff-white solid.
ColorWhite to Off-White
pKa10.16±0.10(Predicted)
Storage Condition-20°C Freezer
MDLMFCD26142648

ceritinib - Introduction

LDK378 is a potent ALK inhibitor with an IC50 of 0.2 nM, acting on IGF-1R and InsR with a selectivity of 40 and 35 times, respectively.
Last Update:2022-10-16 17:11:39
ceritinib
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MedChemExpress (MCE)
Multiple SpecificationsSpot supply
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CAS: 1032900-25-6
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CAS: 1032900-25-6
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: LDK378 Visit Supplier Webpage Request for quotation
CAS: 1032900-25-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: LDK378 Visit Supplier Webpage Request for quotation
CAS: 1032900-25-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: LDK378 Visit Supplier Webpage Request for quotation
CAS: 1032900-25-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
ceritinib
1-(2-Propenyl)-1,2,3,4-tetrahydro-6-bromo-2,4-dioxoquinazoline-3-acetic acid
108213-17-8
4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(ethoxymethyl)phenol hydrochloride
28221-82-1
2-(4-Methoxyphenyl)-2-phenyl-1,3-dioxolo[4,5-c]quinolin-4(5H)-one
3-Iodopyridine-2-Carboxylic Acid Methyl Ester
1017785-80-6
253440-88-9
56128-29-1
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