2-(4-Chloro-3-methylphenoxy)acetohydrazide is an organic compound with the chemical formula C10H12ClN3O2. It had the appearance of a white crystalline solid. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 243.68g/mol
-Melting point: 135-138°C
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol, ether and acetone.
Use:
- 2-(4-Chloro-3-methylphenoxy)acetohydrazide have certain biological activities in the field of medicine. It is used as a starting material for the synthesis of guanidine compounds and as an intermediate for antitumor and antidepressant drugs.
-It is also used as an intermediate for pesticides and has insecticidal activity.
Preparation Method:
2-(4-Chloro-3-methylphenoxy)acetohydrazide can be synthesized by the following steps:
1.2-(4-chloro-3-methylphenoxy) acetic acid reacts with hydrazine under alkaline conditions to generate the corresponding acetohydrazide product.
2. The reaction product is purified by crystallization and dried to obtain the target compound.
Safety Information:
There is limited information on the toxicity of the -2-(4-Chloro-3-methylphenoxy)acetohydrazide, but it may have some potential danger to humans. Therefore, the use of the compound requires appropriate laboratory safety measures to avoid contact with the skin, eyes and respiratory system.
-Wear appropriate protective equipment, including laboratory gloves, goggles and face shields, when operating.
-Waste should be disposed of in accordance with local regulations and should not be dumped or discharged into the environment.