V

V - Names and Identifiers

Name	3-O-D-glucopyranosyl( 1→4)- [ L-rhamnopyranosyl(1→2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid – 28-O-rhamnopyranosyl(1→4)glucopyranosyl(1→6)glucopyranoside
Synonyms	V Hederacolchiside F Pulsatillasaponin H Hederacholichiside F Pulsatillasaponin III 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid 3-O-D-glucopyranosyl( 1→4)- [ L-rhamnopyranosyl(1→2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid – 2 3-O--D-glucopyranosyl(1→4)-[-L-rhaMnopyranosyl(1→2)]--L-arabinopyranosyl23-hydroxyllup-20(29)-en-28-oicacid–28-O-rhaMnopyranosyl(1→4)glucopyranosyl(1→6)glucopyranoside 3-O-D-glucopyranosyl( 1→4)- [ L-rhamnopyranosyl(1→2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid – 28-O-rhamnopyranosyl(1→4)glucopyranosyl(1→6)glucopyranoside
CAS	68027-14-5

V - Physico-chemical Properties

Molecular Formula	C65H106O31
Molar Mass	1383.53
Density	1.53±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point	205-208℃
Specific Rotation(α)	-9 (Py)
Solubility	Soluble in methanol, acetonitrile, ethanol and other solvents, insoluble in petroleum ether.
Appearance	White crystal
pKa	12.50±0.70(Predicted)
Storage Condition	2-8℃
Sensitive	Easily absorbing moisture

V - Introduction

3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside is a compound naturally occurring in Pulsatilla plants, belonging to the saponins. It is mainly found in the roots, stems and leaves of the Pulsatilla plant. 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside has the formula C57H92O28 and a molecular weight of 1167.3g/mol.

3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside has a variety of biological activities, including antibacterial, anti-inflammatory and antioxidant effects. It is also widely used in traditional herbal medicine to treat diseases such as rheumatism, arthritis and pain.

According to the preparation method, 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside can be obtained from Pulsatilla plants. First, the Pulsatilla plant material is ground to a powder and extracted with a solvent such as ethanol. Then through the steps of solvent evaporation and recrystallization, the high purity 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29) can be obtained.-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside.

For safety information, 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside is generally considered to have good safety at regular dosages. But long-term or high-dose use may cause some side effects, such as gastrointestinal discomfort or allergic reactions. When using 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside should be used with caution and preferably under the guidance of a doctor, especially for pregnant women, lactating women and people with other health problems.

Overall, 3-O-D-glucopyranosyl( 1 → 4)- [ L-rhamnopyranosyl(1 → 2)]-L-arabinopyranosyl 23-hydroxyl lup-20(29)-en-28-oic acid-28-O-rhamnopyranosyl (1 → 4)glucopyranosyl (1 → 6)glucopyranoside is a natural compound with various biological activities, which can be used in traditional herbal medicine and has certain medicinal value. But before use should understand its production and safety information, and use with caution.

Last Update：2024-04-10 22:29:15