Molecular Formula | C9H11ClN4O2 |
Molar Mass | 242.66 |
Density | 1.71±0.1 g/cm3(Predicted) |
Solubility | DMSO: < 0.05 mg/mL |
pKa | 7.06±0.10(Predicted) |
Storage Condition | -20℃ |
In vitro study | Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase. The combination of Trifluridine and Tipiracil is a new oral treatment for metastatic colorectal cancer. Tipiracil prevents degradation of FTD through a first-pass effect as a thymidine phosphorylase inhibitor. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.121 ml | 20.605 ml | 41.21 ml |
5 mM | 0.824 ml | 4.121 ml | 8.242 ml |
10 mM | 0.412 ml | 2.06 ml | 4.121 ml |
5 mM | 0.082 ml | 0.412 ml | 0.824 ml |