Scopoline(Scopoline) is a natural organic compound with the chemical formula C7H9NO. It is a base with a heterocyclic structure and belongs to a member of the scopolamine family.
Scopoline is commonly used in drug research and preparation. It has anticholinergic activity, so it is widely used in the field of biomedicine, especially as an intermediate for drugs such as atropine and scopolamine. It can also be used to synthesize other drugs and chemicals, such as antipsychotic drugs.
Scopoline can be prepared by a variety of methods. One common method of preparation is by hydrogenolysis of the natural product scopolamine. Specifically, scopolamine is reacted with an alkyd ester of sodium hydroxide and subjected to hydrogenolysis under alkaline conditions to give Scopoline.
Regarding safety information, Scopoline can irritate the eyes, respiratory system and skin, so care should be taken to avoid contact during use. At the same time, it also has a certain degree of toxicity, so it should follow the relevant safety practices, such as wearing protective glasses and gloves, and operating in a well-ventilated environment.