RWJ-51204

Name	RWJ-51204
Synonyms	RWJ-51204 Pyrido[1,2-a]benzimidazole-4-carboxamide, 5-(ethoxymethyl)-7-fluoro-N-(2-fluorophenyl)-1,2,3,5-tetrahydro-3-oxo-
CAS	205701-85-5

Molecular Formula	C21H19F2N3O3
Molar Mass	399.39
Density	1.41±0.1 g/cm3(Predicted)
Boling Point	533.0±50.0 °C(Predicted)
Solubility	DMSO
pKa	10.81±0.70(Predicted)
Storage Condition	-20℃
In vitro study	RWJ-51204 binds to receptors in the cerebral cortex, cerebellum, or medulla-spinal cord with K i ranging from 0.2 to 0.6 nM.
In vivo study	RWJ-51204 is orally active in anxiolytic efficacy tests. WJ 51204 dose-relatedly antagonizes PTZ-induced clonic convulsions when administered orally (ED 50 = 0.04 mg/kg). RWJ-51204 is effective in the conflict test in monkeys (ED 50 of approximately 0.5 mg/kg p.o.). RWJ-51204 potently impairs rotarod performance in rats (ED 50 = 0.12 mg/kg), and all rats given RWJ-51204 orally at 30 mg/kg exhibit sedation, reduced skeletal muscle tone, and impairment of rotarod performance.

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CAS: 205701-85-5
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Product Name: RWJ-51204 Visit Supplier Webpage Request for quotation
CAS: 205701-85-5
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Mobile: +86-18621343501
QQ: 2881950922

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Product Name: RWJ-51204 Visit Supplier Webpage Request for quotation
CAS: 205701-85-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328

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Product Name: RWJ-51204 Visit Supplier Webpage Request for quotation
CAS: 205701-85-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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