Molecular Formula | C17H21NO3 |
Molar Mass | 287.35 |
pKa | pKa 9.0 (Uncertain) |
Physical and Chemical Properties | Chemical properties white crystals. Melting point 88-90 ℃. |
Use | Introduction Ritodrine is an adrenergic β2 receptor agonist used to prevent premature delivery. The effects of the drug on pregnant women include arrhythmia, pulmonary edema, rhabdomyolysis, mumps, neutropenia, acute generalized exupetic pustulosis, nausea and vomiting, and elevated blood sugar. |
Pharmacological action
ritodrine hydrochloride is a β2-receptor agonist. This product has a direct sympathomimetic effect, and its β2-receptor effect is outstanding, and it is similar to sardin wave. It can inhibit the swelling force of the smooth muscle of the sub-official, so that the uterus can reduce the contraction force to achieve the effect of pregnancy. In addition, it can accelerate the maturation of the fetus.
Indications
Ritodrine hydrochloride is an adrenergic β2 receptor agonist used to prevent premature delivery.
Contraindications
Bleeding, pregnancy induced hypertension syndrome, and recording collapse are contraindicated.
Side effects
The effects of Ritto hydrochloride on pregnant women include arrhythmia, pulmonary edema, rhabdomyolysis, mumps, granulocytopenia, acute generalized exuberant pustulosis, nausea and vomiting, and elevated blood sugar. The mechanism of the above adverse reactions may be related to the electrolyte imbalance caused by ritodrine hydrochloride, the decrease of blood potassium, the change of pulmonary capillary wedge pressure, the transient ischemia of muscle caused by hypokalemia, the increase of salivary amylase secretion, bone marrow suppression, and the promotion of glycogen decomposition.