Propargyl-PEG4-Osu
Propargyl-PEG5-NHS ester
CAS: 1393330-40-9
Molecular Formula: C18H27NO9
Propargyl-PEG4-Osu - Names and Identifiers
Propargyl-PEG4-Osu - Physico-chemical Properties
| Molecular Formula | C18H27NO9 |
| Molar Mass | 401.41 |
| Density | 1.23±0.1 g/cm3(Predicted) |
| Boling Point | 497.6±55.0 °C(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Propargyl-PEG4-Osu - Reference Information
| biological activity | Propargyl-PEG5-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Propargyl-PEG5-NHS ester can be used to synthesize a series of PROTAC molecules. Propargyl-PEG5-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | Cleavable PEGs Alkyl/ether |
| in vitro research | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 15:16:37
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View History
Propargyl-PEG4-Osu
326903-32-6
3-FLUOROVALINE
(3E)-5-amino-3-[[4-[[4-[(2,4-diaminophenyl)diazenyl]phenyl]sulfamoyl]phenyl]hydrazinylidene]-6-[(4-nitrophenyl)diazenyl]-4-oxonaphthalene-2,7-disulfonate
3-(4-(1-hydroxy-2-methoxyethyl)phenoxy)-1-(isopropylamino)-2-propanol
326903-32-6
3-FLUOROVALINE
(3E)-5-amino-3-[[4-[[4-[(2,4-diaminophenyl)diazenyl]phenyl]sulfamoyl]phenyl]hydrazinylidene]-6-[(4-nitrophenyl)diazenyl]-4-oxonaphthalene-2,7-disulfonate
3-(4-(1-hydroxy-2-methoxyethyl)phenoxy)-1-(isopropylamino)-2-propanol