PhenylHquinazolinone - Names and Identifiers
PhenylHquinazolinone - Physico-chemical Properties
Molecular Formula | C14H10N2O
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Molar Mass | 222.24 |
Density | 1.19 |
Melting Point | 138-140°C |
Boling Point | 391.1±25.0 °C(Predicted) |
Flash Point | 190.3°C |
Vapor Presure | 2.53E-06mmHg at 25°C |
pKa | 2.00±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.646 |
MDL | MFCD00024102 |
PhenylHquinazolinone - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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PhenylHquinazolinone - Introduction
3-Phenyl-4-(3H)quinazolinone, also known as 4-phenylquinolinone, is an organic compound. Its chemical formula is C16H11NO and its molecular weight is 237.26g/mol. Some of its properties are as follows:
1. Appearance: 3-Phenyl-4-(3H)quinazolinone is white to light yellow crystal powder.
2. Solubility: It can be dissolved in organic solvents, such as ethers, ketones and chlorinated hydrocarbons, but its solubility in water is low.
3. Melting Point: about 156-160 degrees Celsius.
4. Chemical Properties: 3-Phenyl-4-(3H)quinazolinone is a compound with aromatic properties and neutral properties.
About its use:
1. Drug research: 3-Phenyl-4-(3H)quinazolinone is a commonly used intermediate, which can be used to synthesize a variety of drugs, such as antibacterial agents, antiviral agents and anti-tumor drugs.
2. Chemical Synthesis: it can be used as an important raw material in organic synthesis, participate in various synthetic reactions, such as carbonylation reaction, carbamylation reaction and suspension silver reaction.
Preparation Method:
1. Synthesis of Aromatic ketones: 3-Phenyl-4-(3H)quinazolinone was synthesized by aromatic carbonylation using benzoic acid and ethyl acetate as raw materials under appropriate reaction conditions.
Safety Information:
1. 3-Phenyl-4-(3H)quinazolinone has limited toxicity data, please use it in strict accordance with laboratory operation specifications.
2. There may be eye, skin and respiratory tract irritation, should pay attention to avoid contact. Use appropriate protective equipment such as gloves, goggles and protective masks.
3. Should be stored in a cool, ventilated place, avoid direct sunlight and high temperature.
Please note that the above information is for reference only. When using 3-Phenyl-4-(3H)quinazolinone, safe operation should be carried out according to the actual situation and professional recommendations.
Last Update:2024-04-09 21:54:55