Peiminine
Peiminine
CAS: 18059-10-4
Molecular Formula: C27H43NO3
Peiminine - Names and Identifiers
| Name | Peiminine |
| Synonyms | PEINININE Peiminine PEIMININE RADDEANINE Osnovanine PEIMINE (RG) Fritillarine 3beta,20-Dihydroxy-5alpha-cevan-6-one Cevan-6-one,3,20-dihydroxy-, (3β,5α)- (3beta,5alpha)-3,20-dihydroxycevan-6-one N-(cyclohexylmethyl)-5-phenyl-1-pentanamine |
| CAS | 18059-10-4 |
| InChI | InChI=1/C27H43NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-23,25,29,31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23-,25-,26+,27-/m0/s1 |
Peiminine - Physico-chemical Properties
| Molecular Formula | C27H43NO3 |
| Molar Mass | 429.64 |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Melting Point | 267° |
| Boling Point | 567.1±50.0 °C(Predicted) |
| Specific Rotation(α) | D22 -38.5° (c = 1.5 in chloroform) |
| Solubility | DMSO : ≥ 100 mg/mL (232.75 mM) |
| Appearance | White cluster crystal (crystal) |
| Color | White to Off-White |
| pKa | 14.56±0.70(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
| Refractive Index | 1.585 |
| MDL | MFCD00210542 |
| Physical and Chemical Properties | It is derived from Fritillaria. |
Peiminine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29389090 |
Peiminine - Reference
| Reference Show more | 1. Chen Que, Wang Yuanbiao, Liu Zhengqiong, et al. Screening, Identification and Antimicrobial Activity Determination of Alkaloid-Producing Endophytic Fungi of Fritillaria from Gansu Province. Chinese Agronomy Bulletin 2012. 2. Han Hongping, Zheng Hongma Tianyi, et al. Molecular Imprinting-Chemiluminescence Sensor Determination of Fritillaria B [J]. Chemical Reagent 2016 038(011):1081-1085. 3. Sun Haifeng, shen Ying. Study on Optimization of Extraction Process of Total Alkaloids from Fritillaria ussura [J]. Chemical Engineer, 2018, 32(4): 9-11. 4. Chen Que, Wang Yuanbiao, Liu Zhengqiong, et al. Screening of Endophytic Fungi Producing Alkaloids from Fritillaria ussura and Determination of Antimicrobial Activity of Alkaloids [J]. Chinese Journal of Antibiotics, 2012. 5. Yutian, Lian Xinjie, Sun Youling, et al. Content analysis of Fritillaria thunbergii origin and its ex-situ introduction [J]. Journal of Chengdu University (Natural Science Edition), 2018, 37(04):36-38 49. 6. Cheng Bin, Zhou Aizhen, Peng Xin, Wang Xinlei, Wang Juan. Establishment of UPLC-Q-TOF-MS/MS Fingerprint of Fritillaria thunbergii and Analysis of Anti-inflammatory Quality Markers [J]. Chinese Pharmacy, 2020,31(17):2129-2135. 7. Wu Xiao. HPLC-ELSD Determination of Alkaloid Active Components in Fritillaria thunbergii after Mutation Breeding [J]. Ginseng Research, 2020,32(05):43-46. 8. Chen G, Liu J, Jiang L, Ran X, He D, Li Y, Huang B, Wang W, Liu D, Fu S. Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways. International Journal of Molecular Sciences. 2018; 9. [IF = 4.183] Guangxin Chen et al."Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways." Int J Mol Sci. 2018 Mar;19(3):821 10. [IF = 5.645] Ning Sui et al."Estimating Fritillaria thunbergii Miq. yield, quality, and potassium use efficiency in response to potassium application rate." Ind Crop Prod. 2021 Jun;164:113409 11. [IF = 3] Qu Lala et al."Phenotypic assessment and screening of ETA/ETB receptors with label-free dynamic mass redistribution say." N-S Arch Pharmacol. 2020 Jun;393(6):937-950 12. [IF = 5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology." PHYTOMEDICINE. 2022 Jul;102:154177 |
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View History
Peiminine
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(2S)-2-[5-(dimethylamino)naphthalene-1-sulfonamido]pentanoic acid
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66508-84-7
38953-85-4
832740-62-2
(2S)-2-[5-(dimethylamino)naphthalene-1-sulfonamido]pentanoic acid
2-Chloro-3,4-diamino-5-bromopyridine
1588404-31-2
Zilantel