PLX-3397
Pexidartinib
CAS: 1029044-16-3
Molecular Formula: C20H15ClF3N5
PLX-3397 - Names and Identifiers
PLX-3397 - Physico-chemical Properties
| Molecular Formula | C20H15ClF3N5 |
| Molar Mass | 417.8148 |
| Density | 1.458±0.06 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 30 mg/mL |
| Appearance | Form solid, color White |
| pKa | 12.81±0.40(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| Physical and Chemical Properties | Bioactive Pexidartinib (PLX3397) is an orally effective multi-target CSF-1R,Kit (c-Kit), and FLT3 receptor tyrosine kinase inhibitor with IC50 of 20 nM, 10 nM, and 160 nM, respectively. Pexidartinib (PLX3397) can induce apoptosis and necrosis and has antitumor activity. Phase 3. |
PLX-3397 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.393 ml | 11.967 ml | 23.934 ml |
| 5 mM | 0.479 ml | 2.393 ml | 4.787 ml |
| 10 mM | 0.239 ml | 1.197 ml | 2.393 ml |
| 5 mM | 0.048 ml | 0.239 ml | 0.479 ml |
Last Update：2024-01-02 23:10:35
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Featured ProductsSpot supply
Product Name: Pexidartinib (PLX3397) Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: PLX-3397 Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Pexidartinib (PLX3397) Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Pexidartinib Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Pexidartinib Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
PLX-3397
(2,4,5-trichlorophenoxy)-3,6-d2 acetic acid
3-FLUORO-2-HYDROXYBENZOIC ACID(3-FLUOROSALICYLIC ACID)
Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, hydrazide (9CI)
2-methyl-3-acetoxy benzoic acid(3-acetoxy -2-methylbenzoic acid)
2-FLUORO-[1,1-BIPHENYL]-4-MAGNESIUMBROMIDE
Ketorolac R-IsoMer
(2,4,5-trichlorophenoxy)-3,6-d2 acetic acid
3-FLUORO-2-HYDROXYBENZOIC ACID(3-FLUOROSALICYLIC ACID)
Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, hydrazide (9CI)
2-methyl-3-acetoxy benzoic acid(3-acetoxy -2-methylbenzoic acid)
2-FLUORO-[1,1-BIPHENYL]-4-MAGNESIUMBROMIDE
Ketorolac R-IsoMer