Name | 4-Nitrobenzhydrazide |
Synonyms | P-NITROBENZHYDRAZIDE 4-Nitrobenzhydrazide P-NITROBENZOHYDRAZIDE 4-nitrobenzohydrazide 4-Nireobenzoylhydrazine ρ-Nitrobenzoyl hydrazine 4-Nitrobenzoic hydrazide p-Nitrobenzoic hydrazide 4-Nitrobenzoyl hydrazide p-nitrobenzoicacidhydrazide 4-Nitrobenzoic acid hydrazide p-Nitrobenzoic acid hydrazide Benzoicacid,4-nitro-,hydrazide 2,5-dihydro-3H-imidazo[1,2-b]pyrazole |
CAS | 636-97-5 |
EINECS | 211-271-1 |
InChI | InChI=1/C7H7N3O3/c8-9-7(11)5-1-3-6(4-2-5)10(12)13/h1-4H,8H2,(H,9,11) |
Molecular Formula | C7H7N3O3 |
Molar Mass | 181.15 |
Density | 1.3539 (rough estimate) |
Melting Point | 210-214 °C |
Boling Point | 292.97°C (rough estimate) |
Solubility | acetone: soluble0.5g/10 mL, clear, yellow |
Appearance | crystals |
Color | Yellow |
Maximum wavelength(λmax) | ['267nm'] |
BRN | 519882 |
pKa | 2.77, 11.17(at 25℃) |
Refractive Index | 1.5860 (estimate) |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | DH5670000 |
TSCA | Yes |
HS Code | 29280000 |
Hazard Class | IRRITANT |
pH range of acid-base indicator discoloration | Colorless (8.2) to yellow (9.5) |
Main application | rosion inhibitor, discernant, cosmetics, paints tooth paste, mouthwash, artificial agent, antituberculosis agent |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Application | 4-nitrobenzoylhydrazine can be used as an internal standard, for the determination of isoniazid in human plasma by the LC-MS/MS method. |
production method | 15% G of p-nitrobenzyl acetate was dissolved in of hot methanol, stirred, and 380g of sodium hydroxide solution was slowly added. After addition, it was placed for 5min and poured into ice water to precipitate. The filtered precipitate was decolorized by adding activated carbon to hot water and recrystallized to obtain 110-121g of p-nitrobenzyl alcohol. |
category | toxic substances |
toxicity grade | high toxicity |
Acute toxicity | intravenous-mouse LD50: 56 mg/kg |
flammability hazard characteristics | open flame flammable; High thermal decomposition releases toxic nitrogen oxide smoke |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature, separate storage of food additives |
fire extinguishing agent | carbon dioxide, foam, sand, water mist |