Molecular Formula | C20H17NO5 |
Molar Mass | 351.35 |
Density | 1.44±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 200-201℃ |
Boling Point | 611.5±55.0 °C(Predicted) |
Solubility | Insuluble (1.8E-3 g/L) (25 °C) |
Appearance | Powder |
Color | Pale Yellow to Yellow |
pKa | -1.62±0.20(Predicted) |
Storage Condition | Refrigerator, under inert atmosphere |
MDL | MFCD00189453 |
Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Alkaloid from Arcangelisia gusanlung, Berberis lambertii, other Berberis spp. and Mahonia japonica. |
Reference Show more | 1. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:// 2. [IF=4.268] Fan Wu et al."A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via PI3K/Akt/FoxO1 signaling pathway."Phytomedicine. 2021 Mar;83:153487 3. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820 4. [IF=3.645] Zhihui Li et al."Identification of components and metabolites in plasma of type 2 diabetic rat after oral administration of Jiao-Tai-Wan using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry."J Sep Sci. 2020 Jul;43(13): |
biological activity | Berlambine is a natural alkaloid. |
Use | for content determination/identification/pharmacological experiments. |