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OSI-420Free Base

OSI-420, Free Base (Desmethyl Erlotinib)

CAS: 183321-86-0

Molecular Formula: C21H21N3O4

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OSI-420Free Base - Names and Identifiers

Name OSI-420, Free Base (Desmethyl Erlotinib)
Synonyms OSI-420
Erlotinib-10
OSI-420Free Base
OSI-420 impurity
6-O-Desmethyl Erlotinib
Erlotinib 6-O-Desmethyl Metabolite
Erlotinib Hydrochloride iMpurity 9
Erlotinib O-Desmethyl Metabolite Isomer
OSI-420, Free Base (Desmethyl Erlotinib)
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)
2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quizolin-6-yl)oxy)ethan-1-ol
CAS 183321-86-0

OSI-420Free Base - Physico-chemical Properties

Molecular FormulaC21H21N3O4
Molar Mass379.41
Density1.30
Melting Point140-142°C
Storage Condition-20°C Freezer
In vivo study Desmethyl Erlotinib exhibits t 1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats.

OSI-420Free Base - Introduction

OSI-420 Free Base is a compound with the chemical name 1-(4-amino-3-oxo-6-(4-(2-(6-(trifluoromethyl) aryl)) ethylamino) phenyl) hexahydro-2H-pyran-2-yl) ethanone. The following is an introduction to the nature, use, method and safety information of OSI-420 Free Base:

Nature:
-Appearance: White to light yellow solid.
-Melting point: About 110-116 ℃.
-Solubility: OSI-420 Free Base is soluble in organic solvents, such as ethanol, acetone and dichloromethane.

Use:
- OSI-420 Free Base is an anti-tumor drug used in cancer treatment research. It is a multi-targeted tyrosine kinase inhibitor and has anti-angiogenic and anti-tumor activities.

Preparation Method:
-The preparation of OSI-420 Free Base has not been publicly disclosed in the literature. In General, methods for preparing such compounds may involve organic synthesis and chemical reactions.

Safety Information:
- OSI420-Free Base is a laboratory synthetic drug, limited to research use.
-Standard laboratory safety practices and personal protective measures should be followed for the use and handling of OSI-420 Free Base.
-specific safety information, such as toxicity, corrosivity and environmental impact needs to be referred to the safety data form (SDS) provided by the chemical supplier.
Last Update:2024-04-09 20:02:46
OSI-420Free Base
Supplier List
MedChemExpress (MCE)
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Product Name: OSI-420 free base; CP-373420 Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
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CAS: 183321-86-0
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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CAS: 183321-86-0
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 183321-86-0
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Email: Int06@meryer.com
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Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple Specifications
Product Name: OSI-420, Free Base (Desmethyl Erlotinib) Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: OSI-420 free base; CP-373420 Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: Desmethyl Erlotinib Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Desmethyl Erlotinib Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Desmethyl Erlotinib Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple Specifications
Product Name: OSI-420, Free Base (Desmethyl Erlotinib) Visit Supplier Webpage Request for quotation
CAS: 183321-86-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
OSI-420Free Base
N-(3-丁烯)氨基甲酸苄酯
BENZYLTRIMETHYLSILANE 苄基三甲基硅烷
二丁基二甲氧基锡
二乙烯三胺五甲叉膦酸五钠
4-(4-甲氧基苯基)-丁醇
四异丙氧基双(二辛基亚磷酸酰氧基)钛酸酯
4-甲基苯甲酰氯
三氟乙酸(4-硝基苯基)酯
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