O-Succinimidyl-1,3-dimethylpropyleneuronium - Names and Identifiers
Name | O-Succinimidyl-1,3-dimethylpropyleneuronium hexafluorophosphate
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Synonyms | HPD-OSU O-Succinimidyl-1,3-d O-Succinimidyl-1,3-dimethylpropyleneuronium O-Succinimidyl-1,3-Dimethylpropyleneuronium O-SUCCINIMIDYL-1,3-DIMETHYLPROPYLENEURONIUM HEXAFLUOROPHOSPHATE O-Succinimidyl-1,3-dimethylpropyleneuronium hexafluorophosphate 2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3,4,5,6-tetrahydro-1,3-dimethylpyrimidinium
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CAS | 443305-32-6
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O-Succinimidyl-1,3-dimethylpropyleneuronium - Physico-chemical Properties
Molecular Formula | C10H16N3O3+
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Molar Mass | 226.26 |
Physical and Chemical Properties | 443305-32-6 |
O-Succinimidyl-1,3-dimethylpropyleneuronium - Introduction
, hexafluorophosphate(O-Succinimidyl-1, O-Succinimidyl-1-activated hexafluorophosphate) is a commonly used ester coupling reagent, mainly used to introduce activated groups into compounds for covalent coupling reactions. The following is a description of the nature, use, preparation and safety information of O-Succinimidyl-1 and hexafluorophosphate:
Nature:
- O-Succinimidyl-1, hexafluorophosphate is a white crystalline solid, soluble in organic solvents such as dimethyl sulfoxide (DMSO), methanol and chloroform.
-It is a stable compound, easy to disperse in solution, and can be activated under neutral conditions.
Use:
- O-Succinimidyl-1, hexafluorophosphate is mainly used as an activated ester coupling reagent and is widely used in the research of biochemistry and medicinal chemistry.
-It can be used to covalently bind biomolecules such as proteins, peptides, antibodies, etc. to other compounds or solid surfaces.
- O-Succinimidyl-1, hexafluorophosphate also have practical applications in chemical crosslinking, hybridization modification and preparation of fluorescent markers.
Preparation Method:
- O-Succinimidyl-1, hexafluorophosphate preparation method is relatively simple, by reacting the corresponding N-methyl-N'-dimethylbiguanide and 1,3-dimethylpropenyl methyl ether, and then reacting with hexaphosphoric acid to obtain the final product.
Safety Information:
-When using O-Succinimidyl-1, hexafluorophosphate, follow laboratory safety procedures and avoid contact with skin, eyes and mucous membranes. In case of accidental contact, rinse immediately with plenty of water and seek medical help if necessary.
-The compound has low toxicity, but it is still necessary to avoid ingestion or inhalation.
-When storing, O-Succinimidyl-1, hexafluorophosphate should be stored in a dry and cool place, avoiding contact with oxygen and water to prevent failure.
Last Update:2024-04-09 15:17:57