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Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine

L-Anserine

CAS: 584-85-0

Molecular Formula: C10H16N4O3

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Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine - Names and Identifiers

Name L-Anserine
Synonyms Anserin
L-Anserine
H-β-Ala-His(3-Me)-OH
L-N-beta-Alanyl-3-methylhistidine
N-beta-alanyl-3-methyl-L-histidine
Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine
2-(3-aminopropanoylamino)-3-(3-methylimidazol-4-yl)-propanoic acid
(S)-2-(4-Aminobutanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
CAS 584-85-0
EINECS 209-545-0

Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine - Physico-chemical Properties

Molecular FormulaC10H16N4O3
Molar Mass240.26
Density1.38±0.1 g/cm3(Predicted)
Melting Point268℃ (decomposition)
Boling Point611.3±55.0 °C(Predicted)
Solubility Soluble (999g/L) (25°C)
AppearanceSolid
ColorWhite to Off-White
pKa3.02±0.10(Predicted)
Storage Condition2-8°C(protect from light)
MDLMFCD11040910
Physical and Chemical PropertiesBioactive Anserine (β-alanyl-N-methylhistidine) is a dipeptide containing β-alanine and 1-methylhistidine. Under normal circumstances, it is not present in human tissues and body fluids, but in serum carnosine deficiency and artificial diet.

Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine - Reference

Reference
Show more
1. Zhu Zhiyi, Zhang Yu, Wang Junhong, etc. Determination of goose carnosine, hypercarnosine and carnosine in meat products by Ion Chromatography-integrated pulsed amperometric detection [J]. Chromatography, 2018, 036(012):1297-1302.
2. Yang Hua, Sun Suling, Chen Weihu, Lu Lizhi, Zhang Yu, Wang Junhong, Zhu Zhiyi, Li Xue, Wang Wei. Comparison and evaluation of nutritional components in muscle of East Zhejiang white geese and Landes geese [J]. Food and machinery, 2020,36(12):28-33.

Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine - Uses and synthesis methods

Target

Human Endogenous Metabolite

In vivo studies

Anserine (drinking water at a concentration of 2.0 g/L (equivalent to 10 mg/mouse); for 8 weeks) completely recoveres the memory deficits, improves pericyte coverage on endothelial cells in the brain, and diminishes chronic glial neuroinflammatory reactions in AβPPswe/PSEN1dE9 Alzheimer's disease (AD) model mice over 18-months old.

Last Update:2024-04-09 19:04:56
Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine
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Mobile: +86-18621343501
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Product Name: L-Anserine Visit Supplier Webpage Request for quotation
CAS: 584-85-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: L-Anserine Visit Supplier Webpage Request for quotation
CAS: 584-85-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
Nα-β-Alanyl-1-dehydro-3-methyl-L-histidine
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