Nilotinib-d6
Nilotinib-d6
CAS: 1268356-17-7
Molecular Formula: C28H16D6F3N7O
Nilotinib-d6 - Names and Identifiers
| Name | Nilotinib-d6 |
| Synonyms | AMN107 D6 Nilotinib-d6 [2H6]-Nilotinib |
| CAS | 1268356-17-7 |
Nilotinib-d6 - Physico-chemical Properties
| Molecular Formula | C28H16D6F3N7O |
| Molar Mass | 535.552760268 |
| Storage Condition | 2-8°C |
Nilotinib-d6 - Introduction
Nilotinib-d6 is an important marker compound and a deuterated derivative of Nilotinib, a therapeutic drug for chronic myeloid leukemia.
Nature:
The chemical formula of Nilotinib-d6 is C28D6H22F3N7O, the relative molecular mass is 582.55, and the appearance is a white crystalline solid. It is a stable deuterated isomer used as an internal standard for nuclear magnetic resonance (NMR).
Use:
Nilotinib-d6 are mainly used in pharmacokinetic studies, bioequivalence analysis and pharmaceutical analysis. Since its deuterated derivative has the same chemical shift in NMR as Nilotinib, it can be used as an internal standard in quantitative analysis and structural confirmation.
Preparation Method:
The preparation of Nilotinib-d6 is usually achieved by chemical synthesis. First, it is necessary to obtain the Nilotinib precursor compound, and then perform a deuteration reaction through an appropriate reaction and deuteration reagent to replace the H atom with the D atom to form the Nilotinib-d6.
Safety Information:
Since Nilotinib-d6 is mainly used as an experimental drug, there are few specific data on its safety. However, based on what is known about Nilotinib, it may have some side effects and toxicity. When used, follow relevant laboratory safety procedures and regulations, and follow appropriate personal protective measures. If necessary, it is recommended to operate and store under suitable laboratory conditions. Before use, consult relevant experts and laboratory safety guidelines.
Nature:
The chemical formula of Nilotinib-d6 is C28D6H22F3N7O, the relative molecular mass is 582.55, and the appearance is a white crystalline solid. It is a stable deuterated isomer used as an internal standard for nuclear magnetic resonance (NMR).
Use:
Nilotinib-d6 are mainly used in pharmacokinetic studies, bioequivalence analysis and pharmaceutical analysis. Since its deuterated derivative has the same chemical shift in NMR as Nilotinib, it can be used as an internal standard in quantitative analysis and structural confirmation.
Preparation Method:
The preparation of Nilotinib-d6 is usually achieved by chemical synthesis. First, it is necessary to obtain the Nilotinib precursor compound, and then perform a deuteration reaction through an appropriate reaction and deuteration reagent to replace the H atom with the D atom to form the Nilotinib-d6.
Safety Information:
Since Nilotinib-d6 is mainly used as an experimental drug, there are few specific data on its safety. However, based on what is known about Nilotinib, it may have some side effects and toxicity. When used, follow relevant laboratory safety procedures and regulations, and follow appropriate personal protective measures. If necessary, it is recommended to operate and store under suitable laboratory conditions. Before use, consult relevant experts and laboratory safety guidelines.
Last Update：2024-04-09 21:04:16
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Spot supply
Product Name: Nilotinib-d6 Visit Supplier Webpage Request for quotationCAS: 1268356-17-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: Nilotinib-d6 Visit Supplier Webpage Request for quotation
CAS: 1268356-17-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1268356-17-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Nilotinib-d6
1-(4-氨基苯基)-N-(4-甲氧基苯基)甲磺酰胺
N'-[(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-2-(2,3,6-trimethylphenoxy)acetohydrazide
4-[(2-Chlorophenyl)[4-(ethylimino)-3-methyl-2,5-cyclohexadiene-1-ylidene]methyl]-N-ethyl-2-methylbenzenamine/molybdic acid/tungstic acid/phosphoric acid,(1:x:y:z)
ART-CHEM-BB B006809
2-(4-bicyclo[2.2.1]hept-2-enyl)ethyl-trimethoxysilane
3,4-DIBROMOINDAZOLE
5-溴-2-(叔丁基二甲氧基硅氧基)嘧啶
反式-1-(叔丁氧羰基)-3-苯基哌啶-4-羧酸
5-溴-2-(2-(哌啶-1-基)乙氧基)吡啶盐酸盐
1-(4-氨基苯基)-N-(4-甲氧基苯基)甲磺酰胺
N'-[(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene]-2-(2,3,6-trimethylphenoxy)acetohydrazide
4-[(2-Chlorophenyl)[4-(ethylimino)-3-methyl-2,5-cyclohexadiene-1-ylidene]methyl]-N-ethyl-2-methylbenzenamine/molybdic acid/tungstic acid/phosphoric acid,(1:x:y:z)
ART-CHEM-BB B006809
2-(4-bicyclo[2.2.1]hept-2-enyl)ethyl-trimethoxysilane
3,4-DIBROMOINDAZOLE
5-溴-2-(叔丁基二甲氧基硅氧基)嘧啶
反式-1-(叔丁氧羰基)-3-苯基哌啶-4-羧酸
5-溴-2-(2-(哌啶-1-基)乙氧基)吡啶盐酸盐