N6-Bz-DMT-Ar - Names and Identifiers
Name | 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine
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Synonyms | N6-Bz-DMT-Ar 5'-DMT-Bz-rA 5'-O-DMT-N6-Bz Adenosine 5'-Dmt-Ribo Adenosine (N-Bz) N6-Benzoyl-5'-O-DMT-adenosine 5'-O-dimethoxytrityl-N6-benzoyl adenosine N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine DTN-006 5'-O-(4,4'-DiMethoxytrityl)-N6-benzoyl-adenosine N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]adenosine N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]adenosine
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CAS | 81246-82-4
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EINECS | 2017-001-1 |
N6-Bz-DMT-Ar - Physico-chemical Properties
Molecular Formula | C38H35N5O7
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Molar Mass | 673.71 |
Density | 1.36 |
pKa | 7.87±0.43(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Use | This product is for scientific research only and shall not be used for other purposes. |
N6-Bz-DMT-Ar - Introduction
5 '-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine, also known as 5 '-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White or off-white solid
-Solubility: Slightly soluble in some polar solvents such as methanol and dichloromethane
-Melting point: about 170-175°C
Use:
-In organic synthesis, it is often used as a protecting group for nucleoside compounds. Through it, a protecting group can be introduced at the corresponding position to protect the active functional group in the reaction, such as hydroxyl or amino.
-As an intermediate in nucleotide synthesis, it can be used to synthesize probes, primers, etc. for RNA or DNA sequences.
Preparation Method:
-A commonly used preparation method is to react adenosine with benzoyl chloride to generate N6-benzoyl adenosine, and then add trityl cation through summation reaction to obtain the final product.
Safety Information:
-No detailed toxicity and injury data are currently reported for this compound. Nevertheless, appropriate laboratory safety measures should generally be taken for any organic synthetic compound, including the wearing of appropriate protective equipment, such as lab gloves and glasses.
-Due to its chemical properties, it may be irritating to the human body, so avoid inhalation and skin contact when in contact. If necessary, the skin or eyes should be cleaned promptly and medical assistance should be sought.
Please note that when using and handling this compound, you should follow the chemical safety procedures and the corresponding safety data sheet.
Last Update:2024-04-09 21:04:16