Boc-D-Lys(Boc)-OH(Boc-D-Lys(Boc)-OH) is a compound whose chemical formula is C18H32N2O6. The properties, use, preparation and safety information of the compound are given below.
Nature:
-Appearance: Colorless or white solid
-Solubility: Soluble in organic solvents such as methanol, dimethyl sulfoxide, insoluble in water
-Melting point: about 80-85°C
-Molecular weight: 376.46g/mol
Use:
- Boc-D-Lys(Boc)-OH is commonly used in organic synthesis as an amino acid protecting group and intermediate.
-During polypeptide and protein synthesis, it is used to protect the amino group in the lysine side chain and deprotect it when needed to ensure selectivity and efficiency.
Preparation Method:
The preparation of Boc-D-Lys(Boc)-OH can be carried out by the following steps:
1. D-lysine reacts with BOC-acid chloride (BOC-Cl) to generate N-BOC-D-lysine.
2. React N-BOC-D-lysine with BOC-Cl again to obtain Boc-D-Lys(Boc)-OH.
3. The product was purified by crystallization to obtain pure Boc-D-Lys(Boc)-OH.
Safety Information:
When using and handling Boc-D-Lys(Boc)-OH, the following safety measures need to be observed:
-Avoid inhalation, ingestion or skin contact with this compound, as it may be harmful to humans.
-During use, keep the room well ventilated to avoid dust.
-Use personal protective equipment such as protective gloves, masks and laboratory clothing.
-When storing and handling the compound, follow relevant chemical safety regulations and keep away from flammable substances.