N-methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine - Names and Identifiers
Name | 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole
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Synonyms | 2-METHYLAMINO-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOL 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole 2-(Methylamino)-5-(trifluoromethyl)-1,3,4-thiadiazole 2-(METHYLAMINO)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE N-methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine N2-Methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine N2-METHYL-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOL-2-AMINE Methyl-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-amine 1,3,4-Thiadiazol-2-amine, N-methyl-5-(trifluoromethyl)-
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CAS | 25366-22-7
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InChI | InChI=1/C4H4F3N3S/c1-8-3-10-9-2(11-3)4(5,6)7/h1H3,(H,8,10) |
N-methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine - Physico-chemical Properties
Molecular Formula | C4H4F3N3S
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Molar Mass | 183.15 |
Density | 1.547g/cm3 |
Melting Point | 115 °C |
Boling Point | 162.7°C at 760 mmHg |
Flash Point | 52.2°C |
Vapor Presure | 2.14mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.51 |
N-methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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Hazard Class | IRRITANT |
N-methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine - Introduction
2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole is an organic compound with the chemical formula C4H5F3N4S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole is a white to yellow crystalline solid.
-Melting point: The melting point of this compound is about 108-111°C.
-Solubility: 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole is easily soluble in many organic solvents, such as alcohols and ketones.
Use:
-Pesticide intermediate: 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole can be used as a pesticide intermediate for the preparation of compounds with fungicidal and insecticidal activity.
-Pharmaceutical research: The compound also has applications in the pharmaceutical field, such as for the synthesis of antibacterial and antitumor drugs.
Method:
The preparation method of 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole can be realized by the following steps:
1.2-amino -5-(trifluoromethyl)-1,3, 4-thiadiazole is reacted with a methylating reagent to carry out a methylation reaction.
2. After the reaction, the target product is purified by crystallization or column chromatography.
Safety Information:
The following safety precautions should be taken when using 2-methylamino-5-(trifluoromethyl)-1,3,4-thiadiazole:
-The compound may be irritating to the eyes and skin. Personal protective equipment such as gloves and goggles should be used when in contact.
-During use, ensure good ventilation conditions and avoid inhaling gas or dust.
-This compound may be harmful to the environment and should be avoided to cause pollution to water, soil or air.
-When using or storing, keep the compound away from fire and oxidizing agents.
Please note that this information is for informational purposes only and follow proper safety procedures when using chemicals.
Last Update:2024-04-09 19:05:48