N-benzyl-N-nitroso-P-toluenesulfonamide - Names and Identifiers
N-benzyl-N-nitroso-P-toluenesulfonamide - Physico-chemical Properties
Molecular Formula | C14H14N2O3S
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Molar Mass | 290.34 |
Density | 1.24g/cm3 |
Melting Point | 85 °C |
Boling Point | 438.7°C at 760 mmHg |
Flash Point | 219.1°C |
Solubility | soluble in Toluene |
Vapor Presure | 6.79E-08mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Yellow |
Storage Condition | Refrigerator |
Refractive Index | 1.596 |
MDL | MFCD00216617 |
N-benzyl-N-nitroso-P-toluenesulfonamide - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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N-benzyl-N-nitroso-P-toluenesulfonamide - Introduction
N-benzyl-N-nitroso-P-toluenesulfonamide is an organic compound with the chemical formula C14H14N2O3S. The following is a description of its nature, use, formulation and safety information:
Nature:
N-benzyl-N-nitroso-P-toluenesulfonamide is a yellow crystalline solid. It is insoluble in water, but soluble in some organic solvents, such as ethanol and benzene. This compound is stable at room temperature.
Use:
N-benzyl-N-nitroso-P-toluenesulfonamide has certain application value in organic synthesis. It can be used as an oxidant and participate in a series of chemical reactions. For example, it can react with anhydrous β-diketones at elevated temperatures to form the corresponding indole derivatives. In addition, the compounds can also be used for the synthesis of amide and ketone compounds.
Method:
N-benzyl-N-nitroso-P-toluenesulfonamide can be prepared by the reaction of benzylamine and sodium nitrite under alkaline conditions. First, benzylamine is reacted with sodium nitrite produced under alkaline conditions to produce the hydrochloride salt of N-benzyl-N-nitrosamine. Then, by reacting with P-Toluenesulfonyl chloride, a N-benzyl-N-nitroso-P-toluenesulfonamide is obtained.
Safety Information:
N-benzyl-N-nitroso-P-toluenesulfonamide should be handled with care to avoid inhalation, ingestion, or contact with skin and eyes. It may irritate the skin, eyes and respiratory system. Therefore, appropriate personal protective equipment, such as laboratory gloves, goggles and protective face masks, should be worn during operation to ensure personal safety. In addition, the compound should be stored in a dry, dark and well-ventilated place, and away from heat sources or flammable materials. After disposal, the remaining chemical waste should be properly disposed of to comply with local environmental regulations.
Last Update:2024-04-10 22:29:15