N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide
Quisinostat (JNJ-26481585)
CAS: 875320-29-9
Molecular Formula: C21H26N6O2
N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide - Names and Identifiers
N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide - Physico-chemical Properties
| Molecular Formula | C21H26N6O2 |
| Molar Mass | 394.47 |
| Density | 1.35 |
| Storage Condition | -20℃ |
| Use | Quisinostat (JNJ-26481585) is a new type of second-generation HDAC inhibitor, which is the most effective for HDAC, with IC50 of 0.11 nM, moderately effective for HDACs 2, 4, 10, and 11; It is 30 times more selective than HDACs 3, 5, 8, and 9, and has the weakest effect on HDACs 6 and 7. |
N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.535 ml | 12.675 ml | 25.35 ml |
| 5 mM | 0.507 ml | 2.535 ml | 5.07 ml |
| 10 mM | 0.254 ml | 1.268 ml | 2.535 ml |
| 5 mM | 0.051 ml | 0.254 ml | 0.507 ml |
Last Update：2024-01-02 23:10:35
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CAS: 875320-29-9
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View History
N-Hydroxy-2-(4-((((1-Methyl-1H-indol-3-yl)Methyl)aMino)Methyl)piperidin-1-yl)pyriMidine-5-carboxaMide
DISODIUM IMINODIACETATE HYDRATE
禾草灵-5-羟基
Octanoic acid, 8-[(2-hydroxyethyl)amino]-, 1-octylnonyl ester
1-NITROPYRAZOLE
2,6-二叔丁基混合酚
噻吩并[2,3-c]吡啶-3-羧酸
阿西美辛酰基-Β-D-葡糖苷酸
Acetamide, 2-[2,5-dimethyl-4-(4-morpholinylmethyl)phenoxy]-
Cyclopropanecarboxylic acid, 2-acetyl-2-methyl-, methyl ester (9CI)
DISODIUM IMINODIACETATE HYDRATE
禾草灵-5-羟基
Octanoic acid, 8-[(2-hydroxyethyl)amino]-, 1-octylnonyl ester
1-NITROPYRAZOLE
2,6-二叔丁基混合酚
噻吩并[2,3-c]吡啶-3-羧酸
阿西美辛酰基-Β-D-葡糖苷酸
Acetamide, 2-[2,5-dimethyl-4-(4-morpholinylmethyl)phenoxy]-
Cyclopropanecarboxylic acid, 2-acetyl-2-methyl-, methyl ester (9CI)