Boc-DL-Met-OH, also known as Boc-DL-Met-OH, is an amino acid derivative with a specific structure. Specific properties are as follows:
1. appearance: Boc-DL-Met-OH common appearance is white crystalline powder.
2. Solubility: Boc-DL-Met-OH is soluble in organic solvents such as dimethylformamide (DMF) or dichloromethane (DCM), but insoluble in water.
3. molecular formula: C12H23NO5S
4. Molecular weight: 293.38g/mol
The main use of Boc-DL-Met-OH is as an intermediate in peptide synthesis and organic synthesis. It can be used as a protecting group in peptide synthesis to protect amino groups or phenolic hydroxyl groups in amino acids, thereby controlling the selectivity and yield of the reaction. In addition, it can also be used in drug research and development, biochemical research and other fields.
The preparation method of the Boc-DL-Met-OH is generally the following steps:
1. condensing benzoyl chloride and dimethylformamide to generate N-benzyl dimethylformamide;
2. converting N-benzyl dimethylformamide into N-benzyl-N-dimethylcarbamic acid methyl ester by nitrosylation reaction;
3. react with ethanethiol to generate Boc-DL-Met-OH.
Regarding safety information, the following safety measures should be followed when using chemicals according to routine laboratory practices:
1. Wear appropriate protective clothing and gloves during operation to avoid direct contact with skin or inhalation of dust;
2. Operate in a well-ventilated place to avoid the accumulation of steam or dust in the air;
3. Storage should avoid contact with oxidants or flammable materials, away from fire;
4. If accidentally splashed into the eyes or skin, immediately rinse with plenty of water and seek medical assistance.